Cutaneous manifestations of diabetes mellitus

Bhat, Yasmeen Jabeen; Gupta, Viney; Kudyar, R P

doi:10.4103/0973-3930.33180

Cited by 25 publications

(4 citation statements)

References 7 publications

(10 reference statements)

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“…We found a high prevalence of cutaneous manifestation of T2DM. The prevalence was similar to that in India, Pakistan and Hong Kong which is between 58 to 67% [10,15,16]. Skin infection was the most common cutaneous manifestation of T2DM in our patients, followed by SDWSAD with diabetic dermopathy.…”

Section: Discussionsupporting

confidence: 84%

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Prevalence and factors associated with cutaneous manifestations of type 2 diabetes mellitus

Rasid

Muthupalaniappen

Jamil

2020

Clinical Diabetology

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Background. Type 2 diabetes mellitus (T2DM) is known to cause multiple systemic manifestations. however, there are limited studies describing cutaneous manifestation among T2DM in Malaysia. The objective of this study was to determine the prevalence of cutaneous manifestation among T2DM patients, types of lesions and its associated factors. Methods. A cross-sectional study was conducted among 271 T2DM patients at a primary care clinic in Kuala lumpur. results. More than one third (63.5%) of patients were found to have cutaneous manifestations of T2DM. The most common manifestation was infections (34.7%) followed by Skin Diseases with Weak to Strong Association with Diabetes (SDWSAD) (31.7%), Skin Manifestation of Diabetic Complication (SMDC) (2.2%) and others cutaneous lesions (22.1%). Among the infections, onychomycosis was the commonest type of infection (27.7%) while diabetic dermopathy was the commonest lesion of SDWSAD (29.7%). Males had almost two times the odds of developing cutaneous manifestations of T2DM, compared to females (adjusted odds ratio [AOr]: 1.871, 95% CI: 1.108-3.160; P = 0.019). There was no association between glycemic control and cutaneous manifestations. however, males and those with T2DM duration of five years and more had 2.6 times the odds of developing SDWSAD (AOr: 2.646, 95% CI: 1.506-4.648 P = 0.001) and (AOr: 2.635, 95% CI: 1.107-6.268, P = 0.028) respectively. Those with diabetic neuropathy and peripheral vascular disease (PVD) had very high odds of developing SMDC such as diabetic foot and trophic ulcers (AOr: 23.

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Section: Discussionsupporting

confidence: 84%

“…Skin infection was the most common cutaneous manifestation of T2DM in our patients, followed by SDWSAD with diabetic dermopathy. Infections and diabetic dermopa-thy are common cutaneous disorders associated with diabetes [8,15,16]. Diabetic foot and trophic ulcer were the most common manifestations of SMDC.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and factors associated with cutaneous manifestations of type 2 diabetes mellitus

Rasid

Muthupalaniappen

Jamil

2020

Clinical Diabetology

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“…12 Infections increases the possibility of developing neurovascular and other systemic complications which can give rise to various dermatological manifestations. 13 In the present study, 116 (96.7%) were type 2 diabetes mellitus and 4 (3.3%) were type a diabetes. In a study by Nigam PK et al reported that 82.1% of subjects had type 2 diabetes.…”

Section: Discussionsupporting

confidence: 44%

Dermatological manifestations in diabetes mellitus

Bose¹,

Kumar²

2020

IJCED

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Diabetes mellitus (DM) is the common endocrine disorder, which affects all ages and socioeconomic groups. The prolonged hyperglycemia may responsible for the diabetic complications. Multiple factors contribute to the onset of cutaneous manifestations in diabetes mellitus. The present study aimed tostudy the pattern of various cutaneous manifestations associated with diabetes mellitus. The present study was conducted at Dermatology, Diabetic Clinic of a teaching tertiary care centre hospital. A total of 120 subjects were included in this study. Patients were selected on the basis of dermatological signs and/or symptoms. Detailed history and clinical examination with special emphasis on dermatological complaints and signs was done for all the study subjects. Under aseptic conditions, blood samples were collected and used for the estimation of blood glucose, bacterial infections-Gram stain and isolation of organism by culture, fungal infections- KOH (potassium hydroxide) mount, Gram stain (for Candida) and isolation of organism by culture. Skin biopsies were performed wherever necessary. In the present study, 120 subjects were included from both genders. Pruritus was the predominant symptom observed. Acrochordons, Candidial Balanoposthitis, Tinea Corporis were observed in highest number of patients. Infective dermatoses were observed in 72 (60%) patients. The non-infective dermatoses was reported in 56 (46.7%) patients. On bacterial culture, Pyogenic Ulcer was observed in 4. KOH test and culture were carried on 14 candidal infections and 17 dermatophyte infection and observed KOH mount positive were observed in 11 cases and culture positive was observed in 8 cases. In the present study results indicates pruritus was the most common symptom in diabetic subjects. Infective dermatoses were more common than the non-infective dermatoses. Tinea corporis/cruris was most common clinical entity. 21.6% patients suffered from cutaneous bacterial infections, the most frequently encountered clinical entity being furunculosis. Staphylococcus aureus The commonest non-infective clinical entity was acrochordons(skin tags). Patients with diabetes may develop cutaneous manifestations of diabetic complications. Careful dermatological examination and follow-up of diabetes mellitus patients is required to provide them adequate skin management.

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“…La PDS inicia en áreas distales de las extremidades siguiendo un patrón en "guantes y medias" con síntomas como el adormecimiento, hormigueo, dolor lancinante y, en algunos casos, debilidad muscular. Puede preceder la aparición de lesiones cutáneas y acompañarse de hipohidrosis o anhidrosis (28) , cambios en la transpiración que generalmente afectan las extremidades inferiores, causan xerosis y fisuras en la piel, que favorece el ingreso de patógenos.…”

Section: Neuropatía Diabéticaunclassified

Manifestaciones dermatológicas de la diabetes: clasificación y diagnóstico

Crizón-Díaz

Morales-Cardona

2020

Iatreia

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Se estima que en Colombia hay 2.836.500 adultos con diabetes, una enfermedad con una prevalencia del 8,4 %. La exposición a niveles elevados de glucosa afecta los procesos de proliferación y diferenciación en las células de todos los órganos y tejidos, así mismo en los queratinocitos, fibroblastos y demás células presentes en la piel, alteraciones que ocurren en más de un tercio de los diabéticos y que pueden ser la manifestación inicial de la enfermedad. La frecuencia y presentación de estas dermatosis varía según la población estudiada. La dermopatía diabética, la acantosis nigricans, los fibromas laxos, el prurito y la xerosis son las formas más comunes y se consideran marcadores cutáneos de la diabetes. La presente revisión se enfoca en las manifestaciones dermatológicas específicas y no específicas de la diabetes, así como en las relacionadas con su tratamiento. Estas pueden ser un reflejo del estado metabólico actual o previo del paciente diabético y su oportuna identificación permite orientar el diagnóstico primario, sospechar un estado rediabético u optimizar el tratamiento de la enfermedad en los individuos ya diagnosticados.

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Cutaneous manifestations of diabetes mellitus

Cited by 25 publications

References 7 publications

Prevalence and factors associated with cutaneous manifestations of type 2 diabetes mellitus

Prevalence and factors associated with cutaneous manifestations of type 2 diabetes mellitus

Dermatological manifestations in diabetes mellitus

Manifestaciones dermatológicas de la diabetes: clasificación y diagnóstico

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