Cutaneous Manifestations in Patients with Covid-19 in the Practice of Emergency Medical Care

Плавунов, Н. Ф.; Кадышев, В. А.; Sidorov, A M; Проскурина, Л. Н.; Goncharova, N. A.

doi:10.20514/2226-6704-2020-10-3-223-229

Cited by 5 publications

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References 9 publications

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“…Частота кожных проявлений у инфицированных вирусом SARS-CoV-2, по данным разных источников, в среднем составляет от 0,2% до 19,6% [3,4]. Поражения эпителия слизистых оболочек и кожи на фоне COVID-19 и при постковидном синдроме характеризуются чрезвычайным многообразием [5,6], однако их патогенез не до конца понятен и изучен [4,[7][8][9][10][11], что обуславливает актуальность данной проблемы.…”

Section:  введениеunclassified

Frequency and Nature of Changes in the Skin and Mucous Membranes in Post-COVID-19 Syndrome

Островский,

Зайцева,

Дятлова

2023

Дерматовенерология Косметология

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Цель. Провести анализ клинических случаев изменений кожи и слизистых оболочек после перенесенной новой коронавирусной инфекции. Материалы и методы. В работе представлены результаты изучения частоты и характера изменений кожи и слизистых оболочек при постковидном синдроме у 106 жителей города Гомеля за период с марта по сентябрь 2023 г. Результаты. По результатам исследования была выявлена наибольшая распространенность изменений кожи и слизистых оболочек спустя полгода после тяжелой степени перенесенной новой коронавирусной инфекции у мужчин, статистически значимо увеличивающаяся с возрастом пациентов. Ведущими кожными проявлениями постковидного синдрома у обследованных лиц были сыпь и сухость кожных покровов. Заключение. Оценка накопленных данных позволит определить диагностическую и прогностическую значимость кожной симптоматики у пациентов с постковидным синдромом. Purpose. To analyze clinical cases of changes in the skin and mucous membranes after COVID-19 infection. Materials and methods. The article presents the results of studying the frequency and nature of changes in the skin and mucous membranes in post-COVID-19 syndrome in 106 residents of the city of Gomel for the period from March to September 2023. Results. According to the results of the study, the greatest prevalence of changes in the skin and mucous membranes was revealed six months after the severe degree of COVID-19 infection in menfolk, statistically significantly increasing with the age of patients. The leading skin manifestations of the post-COVID-19 syndrome in the examined individuals were rash and dryness of the skin. Conclusions. Evaluation of the accumulated data will allow to determine the diagnostic and prognostic significance of skin symptoms in patients with post-COVID-19 syndrome.

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Section:  введениеunclassified

Frequency and Nature of Changes in the Skin and Mucous Membranes in Post-COVID-19 Syndrome

Островский,

Зайцева,

Дятлова

2023

Дерматовенерология Косметология

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Acute urticaria in patients with COVID-19

Senchukova

Молодых

Krinitsyna

2022

Russian Journal of Skin and Venereal Diseases

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Information about the epidemiology, clinical features, prevention and treatment of a new coronavirus infection caused by the SARS-CoV-2 virus is continuously updated and updated. The most common clinical manifestations of COVID-19 are hyperthermia, symptoms of intoxication, cough, shortness of breath, decreased sense of smell and taste, less often abdominal pain, vomiting, diarrhea and other extrapulmonary manifestations. The main target of SARS-CoV-2 is type II alveolar cells, which defines lung damage as the main clinical manifestation of COVID-19. Damage to the neurons of the brain and glia leads to neurological symptoms (fever with headaches, loss of sense of smell, taste, ataxia and seizures). Immunological complications leading to cytokine storm syndrome and acute respiratory distress syndrome play a special role in the pathogenesis of COVID-19 coronavirus infection. Recently, clinical observations have been increasingly appearing describing dermatological skin lesions as a variant of the manifestation of COVID-19 coronavirus infection, including at the onset of the disease, i.e. before the appearance of any signs of the disease. The specificity of skin symptoms in COVID-19 has not yet been proven, and some authors use the term unexplained skin manifestations of COVID-19. The article presents a description of clinical cases of acute idiopathic urticaria at the onset of COVID-19, that does not respond to treatment with antihistamines. On the skin of the chest, abdomen, back, buttocks, arms and legs of patients, multiple, edematous, merging, bright pink, various sizes of urticaria were observed, appearing simultaneously with weakness, partial loss of taste, smell, muscle pain, temperature rise to 3839С. Taking a single dose of the glucocorticoid combined drug betamethasone improved the patients condition within a day; in a man on the 7th day and in a woman on the 3rd day of antiviral therapy with favipiravir, all rashes disappeared. In the general blood test after 2 weeks of treatment, a slight negative dynamics was noted: in a man ― absolute leukopenia (3.6109/l), relative lymphocytosis (51%), an increase in ESR up to 28 mm/h, in a woman ― absolute leukopenia (3.4109/l), relative lymphocytosis (57%). The patients were discharged after a month of treatment with antiviral drugs in satisfactory condition with two negative PCR results for COVID-19. The data obtained suggest that acute urticaria that cannot be treated with antihistamines in COVID-19 can be considered one of the variants of the course of a new coronavirus infection (SARS-CoV-2), and require further in-depth study.

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Skin Manifestations of COVID-19 Infection in the Practice of Dermatologist

Сенчукова

Krinitsyna

Mikhailova³

2022

Arhivʺ vnutrennej mediciny

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In early 2020, the World Health Organization announced the emergence of the disease-a new coronavirus infection (COVID-19). High contagiousness and asymptomatic transmission of the virus led to a rapid spread of infection and reached the scale of a pandemic. It was found that the SARSCoV-2 virus is pathogenic to the lower respiratory tract. At the same time, there are extrapulmonary manifestations, including skin rashes, which are characterized by an extreme variety. Some authors describe skin lesions as the first, and sometimes the only, symptom of a new coronavirus infection. Thus, skin manifestations should be carefully evaluated by dermatologists during the examination, especially during the ongoing pandemic.This article presents 6 clinical cases with various skin manifestations in the acute period of COVID-19 infection. The first patients to complain were dermatologists. Rashes on the skin are characterized by a variety and prevalence: polymorphic vasculitis, livedo-angiitis, urticary, spot-papular, papu lo-vesicular, papulo-squamous elements. All cases are united by the presence of the main symptoms of coronavirus infection characteristic of the acute period — hyperthermia, headache, fatigue, myalgia, partial or complete anosmia, ageusia.Thus, the exchange of clinical experience of skin manifestations in COVID-19 infection is extremely relevant during the ongoing pandemic. The analysis of the accumulated data will provide an understanding of the diagnostic significance and the ability to assess the prognosis when observing such patients.

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Cutaneous Manifestations in Patients with Covid-19 in the Practice of Emergency Medical Care

Cited by 5 publications

References 9 publications

Frequency and Nature of Changes in the Skin and Mucous Membranes in Post-COVID-19 Syndrome

Frequency and Nature of Changes in the Skin and Mucous Membranes in Post-COVID-19 Syndrome

Acute urticaria in patients with COVID-19

Skin Manifestations of COVID-19 Infection in the Practice of Dermatologist

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