Cutaneous lymphangiectases after therapy for carcinoma of the cervix-a case with unusual clinical and histological features

Abstract

Secondary lymphangioma (lymphangiectasis) has been reported as a consequence of lymphatic damage. No specific histological criteria can be used to differentiate primary lymphangioma circumscriptum from lymphangiectasis. We describe a woman who developed lymphangiectases on both non-lymphoedematous upper thighs after hysterectomy and radiation therapy for carcinoma of the cervix. This case differs from the secondary lymphangiomas reported previously in that the vascular channels appeared in newly formed adventitial dermis without histological changes in the epidermis.

Acquired lymphangiectasia (‘lymphangioma circumscriptum’) of the vulva a report of eight cases

“…[15][16][17] In addition, the term 'lymphangioma', which properly should be reserved for a benign neoplasm showing lymphatic endothelial differentiation, is often used to describe developmental or hamartomatous abnormalities as well as changes that are more correctly termed secondary or acquired lymphangiectasia. Furthermore, the specific designation 'lymphangioma circumscriptum' has been applied frequently to lesions such as those described herein, and indeed this was the original clinical and pathological diagnosis in many of the cases in our series.…”

Non‐Infective Cutaneous Conditions of the Vulva

“…5.77). Such vesicles, however, may also appear without overt clinical evidence of lymphoedema (Ambrojo et al 1990), and indeed sometimes in the absence of any underlying cause. They may give rise to diagnostic difficulties, being mistaken for warts or other infections.…”

Post-radiotherapy vascular proliferations in mammary skin: A clinicopathologic study of 11 cases

“…[5][6][7][8] Post-radiotherapy vascular proliferations are well-known complications of radiation exposure and show heterogeneous clinical presentations and histopathologic features. The postradiation vascular proliferations in this group with presumably benign behavior have been described under various names in the literature, 2,6,7,[9][10][11][12][13][14][15][16][17][18][19][20][21] with atypical vascular lesions (AVL) being the most widely accepted nomenclature.…”