Cutaneous lesions and disorders in healthy neonates and their relationships with maternal-neonatal factors: a cross-sectional study

Neonatal Birthmarks: A Prospective Survey in 1000 Neonates

“…8,11 The recent study showed significant correlation of the incidence of sebaceous gland hyperplasia that increased with maternal age. 12 However, there were no significant differences in illness during the pregnancy, use of drug supplementation in pregnancy, and delivery type in the former publication. 8 Our study also gathered data of both maternal underlying diseases and maternal complications during pregnancy, nevertheless no significant correlation of maternal conditions to birthmarks and transient skin lesions in newborns was found in the present study.…”

Transient Cutaneous Alterations of the Newborn

“…Catarina Queirós, 1 Mafalda Casinhas Santos, 2 Rita Pimenta, 1 Cristina Tapadinhas, 1 Paulo Filipe 1,3 complex membranous substance comprising 80% water, 10% protein, and 10% lipids, which include barrier lipids such as ceramides, free fatty acids, phospholipids, and cholesterol, partly synthesised by fetal sebaceous glands during the last trimester of pregnancy. 5 In its composition there are also shed lanugo hair and desquamated cells.…”

“…12 Cutis marmorata seems to be associated with lower gestational age and birth weight, which may be associated with the greater vulnerability of these neonates, who are therefore more likely to present with vasomotor instability. 3 This condition must be distinguished from cutis marmorata telangiectatica congenita, which is characterised by a fixed vascular change associated with subtle dermal atrophy. This entity may be associated with limb length discrepancy, vascular, osseous, ocular, and neurologic malformations.…”

“…2 Newborn skin is therefore more vulnerable, although structurally similar to adult skin, and trauma associated with delivery leaves its marks on it. 3 Moreover, newborn skin must rapidly adapt and mature to provide protection against infection, toxins, changes in temperature, and transepidermal water loss, which poses an additional stress. 1 Because of these factors, cutaneous alterations are relatively common in the neonatal period.…”

“…1 Because of these factors, cutaneous alterations are relatively common in the neonatal period. 3 Most of these conditions are physiological, benign, and transient, thus do not require therapy. 4 Nevertheless, they are frequently a cause of concern to parents, who need reassurance about its nature.…”