Cutaneous leishmaniasis in a globetrotting explorer

Imessaoudene, Lynda; Jacobs, Chris; Hunt, William E.

doi:10.1136/bcr-2019-233056

Cited by 1 publication

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References 3 publications

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“…Nasal obstruction was the most reported symptom (57.9%), followed by nasal discharge (34.2%, with epistaxis in 30.8% of these cases). Other symptoms included lacrimal gland obstruction [171] and deafness [161] in one case each. Though lymphadenopathy and/or lymphangitis were reported in 11.1% of patients, lymph node samples were rarely used for the diagnosis (3.6%).…”

Section: Descriptionmentioning

confidence: 99%

Non-Endemic Leishmaniases Reported Globally in Humans between 2000 and 2021—A Comprehensive Review

Rocha¹,

Pereira

Maia³

2022

Pathogens

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Leishmaniases are human and animal parasitic diseases transmitted by phlebotomine sand flies. Globalization is an important driver of the burden and in the current dynamics of these diseases. A systematic review of articles published between 2000 and 2021 was conducted using the PubMed search engine to identify the epidemiology and clinical management of imported human leishmaniases as a fundamental step to better manage individual cases and traveler and migrant health from a global perspective. A total of 275 articles were selected, representing 10,341 human imported cases. Identified drivers of changing patterns in epidemiology include conflict and war, as well as host factors, such as immunosuppression, natural and iatrogenic. Leishmania species diversity associated with different clinical presentations implies diagnostic and treatment strategies often complex to select and apply, especially in non-endemic settings. Thus, diagnostic and management algorithms for medical clinical decision support are proposed. Increased surveillance of non-endemic cases, whether in vulnerable populations such as refugees/migrants and immunocompromised individuals or travelers, could improve individual health and mitigate the public health risk of introducing Leishmania species into new areas.

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Section: Descriptionmentioning

confidence: 99%