Cutaneous involvement in multiple myeloma: a case report with an unusual location

Youssef, M.; Letaief, A.; Elhani, Ichrak; Soua, Y.; Moussa, Adnène; Belhadjali, H.; Amri, M.

doi:10.5070/d32010024252

Dermatology Online Journal

2014

DOI: 10.5070/d32010024252

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Cutaneous involvement in multiple myeloma: a case report with an unusual location

M. Youssef

A. Letaief²,

Ichrak Elhani³

et al.

Abstract: Multiple myeloma (MM) is a rare cancer. Cutaneous involvement is uncommon with fewer than 100 cases described in the literature. We report herein a patient with MM, subtype IgA kappa, with unusual clinical presentation including the lower lip.

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2021

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Cutaneous Multiple Myeloma

Miriyala¹,

Avasthi²

2021

Cureus

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Multiple myeloma is a plasma cell dyscrasia characterized by abnormal bone marrow clonal plasma cells, histological confirmation of plasmacytoma, monoclonal protein in serum or urine, and evidence of endorgan damage. Organ involvement in multiple myeloma manifests as CRAB (hyperCalcemia, Renal insufficiency, Anemia, lytic Bone lesions). Cutaneous complications in multiple myeloma have been reported in many different phenotypes such as cryoglobulinemia rash, bruising, amyloid deposition, and squamous cell carcinoma. However, cutaneous metastasis of multiple myeloma is very rare with fewer than 100 cases described in the literature so far. Here, we present a case of biopsy-confirmed primary cutaneous multiple myeloma. Our case has other less common features of multiple myeloma such as renal amyloidosis and a coexisting malignant melanoma. This case report describes a unique presentation of multiple myeloma to understand the disease better.

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Cutaneous Multiple Myeloma

Miriyala¹,

Avasthi²

2021

Cureus

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Cutaneous involvement in multiple myeloma: a case report with an unusual location

Abstract: Multiple myeloma (MM) is a rare cancer. Cutaneous involvement is uncommon with fewer than 100 cases described in the literature. We report herein a patient with MM, subtype IgA kappa, with unusual clinical presentation including the lower lip.

Cited by 1 publication

References 7 publications

Cutaneous Multiple Myeloma

Cutaneous Multiple Myeloma

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