Cutaneous involvement as the initial presentation of metastatic breast adenocarcinoma - Case report

Abstract

Cutaneous metastasis is an uncommon manifestation of visceral malignancy. It occurs late in the course of the disease but can be a sign of an unknown neoplasm. A case of local cutaneous metastasis by contiguity with breast adenocarcinoma is reported. It presented as initial manifestation and main complaint of a 68-year-old woman, with no family history and negative screening tests for the disease. Biopsies of ulcers which do not heal, persistent hardened erythema and cutaneous nodules of unknown cause must be performed, since the evidence of cutaneous metastasis can be of extreme importance for the diagnosis, staging and prognosis of an internal cancer. In this scenario, the dermatologist plays a fundamental role and should be always attentive to this diagnostic possibility.

Metástasis cutánea de adenocarcinoma de cuello uterino. Reporte de caso

“…Un estudio en autopsias llegó a demostrar la presencia de metástasis cutáneas distantes en el 75% de los casos analizados. El melanoma se considera la primera causa de metástasis cutáneas en varones y la segunda en mujeres (1,2,5,6).…”

“…Las metástasis palpebrales tienen como primarios melanomas y cánceres de mama. La afectación del cuello suele aparecer por extensión directa de ganglios cervicales, teniendo los primarios a nivel de cavidad oral, pulmón o mama (1)(2)(3)(4)(5).…”