Cutaneous inoculation tuberculosis in a healthcare worker: Case report and literature review

Soto-Febres, Fernando; Ballena-López, José Carlos; Alva, D.; Riboty, A.; Léon, Rosa; Chang, Jin; Pérez-Lazo, Giancarlo; Hidalgo, José A.

doi:10.1016/j.idcr.2020.e00788

Cited by 2 publications

(1 citation statement)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…’TB chancre’ identifies the form that results from the entry of mycobacteria through skin or mucosa lesions. It has been largely correlated to occupational exposure in healthcare settings due to injuries with poorly sterilized equipment, but it is also associated with highly risky procedures as tattooing, circumcision, piercing and acupuncture [ 12 ].…”

Section: Mycobacterial Skin Infectionsmentioning

confidence: 99%

Mycobacterial skin infection

Giannotti

Gregori

Matteelli

et al. 2022

Current Opinion in Infectious Diseases

View full text Add to dashboard Cite

Purpose of review The aim of this article is to review the most recent evidences concerning mycobacterial skin infections, limiting the period of literature research to 2020--2021. Recent findings Mycobacterial skin infections include a heterogeneous group of cutaneous diseases. Cutaneous tuberculosis is usually the result of hematogenous dissemination or spread from underlying foci and it must be distinguished from tuberculids, resulting from the immunological reaction to Mycobacterium tuberculosis antigens. Leprosy prevalence was drastically reduced after introduction of multidrug therapy in the 1980 s, but cases are still reported due to underdiagnosis, and animal and environmental reservoirs. Recent advances concentrate in the diagnostic field. Specific guidelines for the treatment of nontuberculous mycobacteria skin infections are missing and surgical procedures may be required. Prognosis is better as compared to nontuberculous mycobacteria lung disease. Rapid laboratory-confirmed diagnosis of Buruli ulcer may be achieved by the IS2404 PCR. Among new drugs, telacebec is promising in terms of potency, shorter duration and tolerability in animal studies. A clinical trial in humans is planned. Summary Mycobacterial cutaneous lesions are nonpathognomonic and clinical suspicion must be confirmed by culture or molecular detection. Long-course multidrug treatment is required based on susceptibility tests. Surgical intervention may also be required. Rehabilitation and psychosocial support reduce long-term physical and mental consequences mostly in Buruli ulcer and leprosy.

show abstract

Section: Mycobacterial Skin Infectionsmentioning

confidence: 99%

Mycobacterial skin infection

Giannotti

Gregori

Matteelli

et al. 2022

Current Opinion in Infectious Diseases

View full text Add to dashboard Cite

show abstract

Primary Multidrug‐resistant Tuberculosis in a Surgeon Secondary to a Needlestick Injury: A Neglected Problem

Yang¹,

Xu²,

Zhang³

et al. 2022

IDR

View full text Add to dashboard Cite

Healthcare workers (HCWs) are highly at risk for tuberculosis (TB) exposure, particularly those in high TB burden countries. Inoculation TB secondary to needlestick injury is uncommon but can occur in HCWs. Herein, we report an unusual case of primary multidrug-resistant tuberculosis (MDR-TB) in a surgeon secondary to a needlestick injury while performing thoracentesis on a TB patient, and the surgeon recovered and returned to work after 22 months of anti-TB treatment. We searched the PubMed database and identified 19 cases of inoculation TB secondary to sharp injury in HCWs including the present case. Those cases highlight that primary inoculation of TB even MDR-TB infection should not be neglected in patients suffered needlestick injury when the sharp instrument suspected or confirmed contaminated with TB. In this situation, if the HCWs need for additional protection or prophylactic anti-TB is worthy of further study.

show abstract

Cutaneous inoculation tuberculosis in a healthcare worker: Case report and literature review

Cited by 2 publications

References 17 publications

Mycobacterial skin infection

Mycobacterial skin infection

Primary Multidrug‐resistant Tuberculosis in a Surgeon Secondary to a Needlestick Injury: A Neglected Problem

Contact Info

Product

Resources

About