Cutaneous Inguinal Scar Endosalpingiosis and Endometriosis

Abstract

Endosalpingiosis and endometriosis represent ectopic growth of the fallopian tube epithelium and endometrial glands and stroma, respectively. Cutaneous endometriosis is a well-known entity, most often presented on scars after gynecological procedures. Cutaneous endosalpingiosis, however, appears to be a rare condition, with only 5 cases described in medical literature thus far. The authors report an unusual case of a woman with combined inguinal endosalpingiosis and endometriosis occurring in the cutaneous scar at the site of previously placed surgical drain, 10 years after myomectomy had been performed. The authors also provide an extensive review of medical literature in English regarding cutaneous endosalpingiosis and endometriosis and discuss their clinical, histopathological, and immunohistochemical features.

Spontaneous Cutaneous Endometriosis of the Umbilicus: A Case Report

“…These symptoms include cyclical pain, sporadic bleeding and a palpable mass [1,3]. The most common physical findings include pigmented (i.e., red, brown, blue, purple) or skin colored papules or multilobulated nodules [1,5]. The majority of the cutaneous lesions range from 1.0 to 9.0 cm [1,5,13,15].…”

“…While cutaneous endometriosis is known to have exceedingly variable clinical presentations, the current literature seems to agree on some commonly noted symptoms. These symptoms include cyclical pain, sporadic bleeding and a palpable mass [1,3]. The most common physical findings include pigmented (i.e., red, brown, blue, purple) or skin colored papules or multilobulated nodules [1,5].…”

“…Cutaneous endometriosis is most commonly diagnosed in women between the ages of 31 and 38 years [1,3,5,[12][13][14]. The disease should be suspected in any female presenting with cyclical pain, pruritus or episodic bleeding originating from a previous surgical scar, the inguinal region or the umbilicus [3,9].…”

“…Spontaneous cutaneous endometriosis of the umbilicus is known as a Villar nodule, first described by Dr. Villar in 1886 [1,5,10]. …”

“…Cutaneous endometriosis represents a non-neoplastic, ectopic growth of endometrial glands and stroma outside the uterine cavity [1][2][3][4]. Daneil Schroen, a German physician, first described endometriosis in 1690 [5].…”