Cutaneous infection with Mycobacterium obuense

Boyd, Alan S.

doi:10.4103/ijmy.ijmy_7_18

Cited by 2 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, this species was later isolated from sputum sample of a patient with a history of non–small cell lung cancer presenting with patchy lung infiltrates [ 16 ]. Additionally, a case of pneumonia with bacteremia caused by M. obuense in a patient with diabetes mellitus and chronic kidney disease [ 10 ], and a case of cutaneous infection after an insect bite in an immunocompetent patient has been reported [ 9 ], indicating its potential pathogenicity. To our knowledge, 3 cases presented above are the only available reports of M. obuense infection in the world, therefore, making our report rare and valuable.…”

Section: Discussionmentioning

confidence: 99%

Disseminated non-tuberculous mycobacterial infection caused by Mycobacterium obuense in an immunocompromised patient: a case report

et al. 2023

View full text Add to dashboard Cite

Background Mycobacterium obuense (M. obuense) is a rapidly growing mycobacterium (RGM) which has been considered nonpathogenic. Here, we report a case of disseminated non-tuberculous mycobacterial (NTM) infection caused by M. obuense in an immunocompromised patient. Case presentation A 16-year-old boy was referred to our hospital due to acute myeloid leukemia. During the treatment of leukemia, the patient exhibited continuous fever, and diffuse miliary nodules with random distribution were found on chest computed tomography. Repeated examinations of bacterial culture tests revealed sputum and urine samples to be smear-positive for acid-fast bacillus, and blood culture from a peripherally inserted central catheter line showed the growth of NTM. The NTM species was identified as M. obuense by mass spectrometry and confirmed by genome sequencing. Combination therapy with amikacin, rifampicin, azithromycin, and moxifloxacin significantly improved the patient’s symptoms and radiological findings. Conclusion We report a case of disseminated NTM infection caused by M. obuense for which combination anti-microbial therapy was effective. An immunocompromised host indwelling catheter is at risk of RGM bloodstream infections. Although relatively rare, M. obuense may be considered as a potential pathogen causing infectious diseases, especially in high-risk patients.

show abstract

Section: Discussionmentioning

confidence: 99%