Cutaneous Horn Malignant Melanoma

Lentigo Malignant Melanoma Presenting with Cutaneous Horn

“…Even though most cutaneous horns are benign, they may superimpose on a malignant lesion 5 . Approximately half of cutaneous horns are associated with benign lesions, and 20% to 30% of cutaneous horns are associated with premalignant keratoses, 3,5 although 20% may overlie squamous cell carcinoma (SCC) or basal cell carcinoma (BCC). The risk of cutaneous horn overlying a malignancy is much higher in elderly fair‐complexioned persons.…”

“…In addition, cutaneous horns are not rare with solar keratosis, BCC, and SCC. It has been said that large or giant cutaneous horns are commonly derived from a malignant base 3 . Excisional biopsy with histologic examination of the base is necessary to determine the best therapy, which would be dictated by the diagnosis of the underlying lesion and by the apparent adequacy of removal 5…”

“…Although there are some cutaneous horn reports associated with BCC, SCC, sebaceous carcinoma, pilomatricoma, and trichilemmal carcinoma in the literature, 9–13 we found only one case report associated with melanoma. Cristobal and colleagues 3 published the first case report defined as verrucous malignant melanoma arising as a cutaneous horn. Their case was a 29‐year‐old woman with a firm, hyperkeratotic, hyperpigmented, conical protrusion surrounded by normal skin on her left leg.…”

“…Cutaneous horns are uncommon lesions in clinical practice. They arise as a variably sized protrusion of keratotic, cohesive material organized in the shape of a conical horn, often located on the face or in sun‐exposed areas 3,4 . These lesions are most often benign, with hyperkeratosis being superimposed on an underlying seborrheic keratosis, verruca vulgaris, angiokeratoma, molluscum contagiosum, or trichilemmoma approximately 60% of the time 5,6 .…”

“…These lesions are most often benign, with hyperkeratosis being superimposed on an underlying seborrheic keratosis, verruca vulgaris, angiokeratoma, molluscum contagiosum, or trichilemmoma approximately 60% of the time 5,6 . It has been found that giant cutaneous horns are commonly derived from a malignant lesion 3 …”