Cutaneous Gamma-delta T-cell Lymphoma with an Initially Indolent Course Mimicking Lupus Panniculitis

Primary Cutaneous Gamma-Delta T-Cell Lymphoma With Long-Term Indolent Clinical Course Initially Mimicking Lupus Erythematosus Profundus

“…The case presented here, however, had been indolent for several years, before suddenly and rapidly progressing. Such a protracted course of disease has previously only been observed in exceptional cases (12)(13)(14). This unusual clinical course further complicates the already difficult clinical and histopathological diagnosis of the disease.…”

Primary Cutaneous Gamma-Delta T-cell Lymphoma: Not an Aggressive Disease in All Cases

“…However, an increasing corpus of reports suggests the existence of a less frequently encountered subset with an allegedly more "indolent" or "smouldering" clinical course, variable clinical and histological presentations (4)(5)(6)(7)(8)(9)(10)(11)(12) and an overall survival that may range from 2 (4) to more than 15 years (10). Of note, the accurate nature of this "indolent" behaviour appears relatively ambiguous in earlier reports, since it may reflect variable underlying considerations including a less-than-expected clinical aggressiveness, a protracted overall survival (usually estimated since first occurrence of skin lesions) and/or a more favourable response to treatment.…”