Cutaneous Eruption due to Telaprevir

Abstract

Hepatitis C virus (HCV) chronically infects 0.5-3% of the world population. A large group of patients develop cirrhosis and its complications. Since 2011, telaprevir and boceprevir are used, improving the disease evolution. One of the main side effects of these drugs is skin eruption. We report a 53-year-old patient with cirrhosis due to HCV who started the classic treatment associated with telaprevir. In the ninth week, he presented a severe rash that required the interruption of this drug. We emphasize the importance of early recognition and appropriate management of adverse skin reaction.

A case of erythema multiforme drug eruption associated with erythrodermic psoriasis induced by sofosbuvir and daclatasvir

“…There are no specific characteristics describing eruption due to SOF and DCV. Other possible related causes should also be investigated to determine the source of the skin lesions . Skin biopsy is also not specific, but it is important for the differential diagnosis process …”