Cutaneous Depth of the Supraorbital Nerve

Christensen, Kate; Lachman, Nirusha; Pawlina, Wojciech; Baum, Christian L.

doi:10.1097/dss.0000000000000174

Cited by 28 publications

(18 citation statements)

References 25 publications

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“…Although electrodes are relatively large to cover the central section of the forehead, the results indicate that when the nerve is shifted away from the center of the forehead, stimulus current threshold level may be increased for all nerve variations. This shows that the relatively mixed results due to the existing design may be attributed to the nerve variations as reported in the literature [11] and implemented in this paper.…”

Section: Discussionmentioning

confidence: 71%

“…The SON and STN trajectories cannot be distinguished from the MRI images due to their relatively small diameters (i.e., ~ 1mm) [3] but they were obtained from the literature [11], [12]. 3D models of the nerves were manually constructed in ScanIP.…”

Section: A Mri Data and Segmentationmentioning

confidence: 99%

“…A trajectory of STN and four variations of SON were constructed to investigate the current threshold for each nerve model. The statistically average nerve position was shifted along the forehead based on reported standard deviations in the literature [11]. These nerves were named as STN, SON1, SON2, SON3 and SON4, where SON4 is the one which is furthest away from the center of the forehead.…”

Section: A Mri Data and Segmentationmentioning

confidence: 99%

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Effect of nerve variations on the stimulus current level in a wearable neuromodulator for migraine: A modeling study

Salkim

Shiraz

Demosthenous

2017

2017 8th International IEEE/EMBS Conference on Neural Engineering (NER)

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Migraine is a socioeconomic burden, whose pharmaceutical and invasive treatment methods may have troublesome side-effects. A wearable neuromodulator targeting frontal nerve branches of trigeminal nerve may provide an effective solution to suppress or treat migraine. Such solutions have had limited efficacies. In this paper, using computational models, the relationship of this lack of efficacy to some neural variations is investigated. The results indicate that due to neuro-anatomic variations, different current levels may be required to achieve a sufficient level of neural stimulation. Thus, an optimized design should consider such variations across the patient group.

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Section: Discussionmentioning

confidence: 71%

Section: A Mri Data and Segmentationmentioning

confidence: 99%

Section: A Mri Data and Segmentationmentioning

confidence: 99%

See 1 more Smart Citation

Effect of nerve variations on the stimulus current level in a wearable neuromodulator for migraine: A modeling study

Salkim

Shiraz

Demosthenous

2017

2017 8th International IEEE/EMBS Conference on Neural Engineering (NER)

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“…Damage to the STN and SON may result in insensibility in the skin of the forehead or tingling and itching (22). Growing neuroma has also been reported after peripheral nerve injury (23)(24)(25). The distance between the exiting point of the STN and the midline was reported in previous studies as 0.866 ± 0.103 cm (10), 1.6 to 2.3 cm (26), and 0.85 to 2.67 cm (2).…”

Section: Discussionmentioning

confidence: 87%

Topographic methods to expose the exiting points of supratrochlear,supraorbital, and zygomaticotemporal nerves

Tezer¹,

Gilan²,

Elvan³

et al. 2017

Turk J Med Sci

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Background/aim: We evaluated the relations of the exiting points of supratrochlear (STN), supraorbital (SON), and zygomaticotemporal (ZTN) nerves with certain landmarks to provide improved anatomic knowledge. Materials and methods: The twenty-eight hemifaces of 5 fresh frozen and 11 embalmed heads (5 female and 11 male cadavers) were dissected. Distance and angular measurements were made between the exiting points of the nerves to the midline, lateral, and medial canthi. Comparisons of side, sex, and cadaver groups were evaluated.Results: Mean values were determined for all parameters. There was no difference between side measurements. There were significant differences between sexes and cadaver groups regarding STN and lateral canthus in both sides. The angle of the ZTN to the lateral canthus was found to be higher in embalmed cadavers than in fresh frozen ones.Conclusion: This study is the first to supply both distance and angular measurements to reach the exact locations of the nerves. Quantitative and topographic information about the localizations of the STN, SON, and ZTN is crucial for forehead lifting and migraine treatment, as well as for injection and local surgical interventions.

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“…The exact nerve trajectories could not be identified in the MRI scans. Therefore, realistic SON and STN nerve trajectories were extracted based on data in [13] and [14]. Combined with Cefaly's electrode patch they were modeled from primitive shapes in ScanIP software.…”

Section: A Realistic Human Head Model Developmentmentioning

confidence: 99%

Effect of model complexity on fiber activation estimates in a wearable neuromodulator for migraine

Salkim

Shiraz

Demosthenous

2017

2017 IEEE Biomedical Circuits and Systems Conference (BioCAS)

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Migraine is a prevalent and highly disabling disorder. The pharmaceutical and invasive treatment methods have troublesome side effects and associated risks, hence undesirable. Transcutaneous supraorbital neuromodulation has been shown to potentially suppress episodic migraine attacks yet results have low efficacy. This inconclusive response may be associated with neuroanatomical variations of patients which may be investigated using computational models. Model complexity is a limiting factor in implementing such techniques. This paper investigates the effect of model complexity on fiber activation estimates in transcutaneous frontal nerve stimulati on. It is shown that the model can be simplified while minimally affecting the outcome.

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Cutaneous Depth of the Supraorbital Nerve

Abstract: The supraorbital nerve depth and course are relevant when performing procedures on the forehead. A thorough understanding of the anatomy and depth of SON-S is critical to help minimize nerve damage and optimize patient counseling.

Cited by 28 publications

References 25 publications

Effect of nerve variations on the stimulus current level in a wearable neuromodulator for migraine: A modeling study

Effect of nerve variations on the stimulus current level in a wearable neuromodulator for migraine: A modeling study

Topographic methods to expose the exiting points of supratrochlear,supraorbital, and zygomaticotemporal nerves

Effect of model complexity on fiber activation estimates in a wearable neuromodulator for migraine

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