Cutaneous arteritis presenting with hyperpigmented macules: macular arteritis

Fein, Howard; Sheth, Anita P.; Mutasim, Diya F.

doi:10.1067/s0190-9622(03)00747-3

Cited by 51 publications

(50 citation statements)

References 11 publications

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“…In the literature, we found 22 cases of MLA [1,2,3,4,5,6,8,9,10,11,12,13,14] (PubMed search for ‘macular arteritis', ‘MLA' and ‘LTA', limits January 2003 to February 2013). This disease mostly affects women (median age: 34 years) often with North African origins.…”

Section: Discussionmentioning

confidence: 99%

“…Macular arteritis [1], lymphocytic thrombophilic arteritis (LTA) [2] and macular lymphocytic arteritis (MLA) [3] (all these terms describe in fact the same disease) constitute a rare and recently described form of cutaneous lymphocytic vasculitis with unique clinicopathological features. It is characterized clinically by erythematous or hyperpigmented, reticulated patches and macules arising preferentially on the lower limbs and histopathologically by a cutaneous lymphocytic medium-sized vessel arteritis.…”

Section: Introductionmentioning

confidence: 99%

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Macular Lymphocytic Arteritis: Three Cases Questioning Its Classification as Primary Lymphocytic Vasculitis

et al. 2013

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Background: Macular arteritis, macular lymphocytic arteritis (MLA) or lymphocytic thrombophilic arteritis all correspond to an identical new clinicopathological entity. Its individualization as a primary cutaneous lymphocytic arteritis is still controversial for certain authors as it could represent a latent form of cutaneous polyarteritis nodosa. Materials and Methods: We report here 3 additional cases of MLA, present a review of the literature and discuss the disease's nosology. Results: MLA is characterized clinically by a benign skin eruption consisting in bilateral asymptomatic erythematous/hyperpigmented macules mainly located on the lower legs and histologically by a medium-sized cutaneous lymphocytic prominent arteritis present in early cutaneous lesions. Conclusion: These findings support that MLA may be considered as a chronic and indolent primary lymphocytic cutaneous arteritis. Nevertheless, in some cases the objective obliteration of cutaneous vessels underlines the need for continuous monitoring in MLA patients.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Macular Lymphocytic Arteritis: Three Cases Questioning Its Classification as Primary Lymphocytic Vasculitis

et al. 2013

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“…In the photomicrographs, a hyalinized ring of fibrin could be seen in the vessel lumina. 25,26 In the study by Fein et al, 25 2 of the 3 patients described had positive titers of anticardiolipin IgG antibodies. We believe that the vasculitic process in these patients is identical to that in the present patients.…”

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confidence: 99%

“…25,26 Clinically, hyperpigmented, reticulated patches and macules were present mainly over the extremities. Histologically, there were dense infiltrates of lymphocytes in the muscular wall of small arteries of the subcutis.…”

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confidence: 99%

Lymphocytic Thrombophilic Arteritis

Lee¹,

Kossard²,

McGrath³

2008

Arch Dermatol

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“…Macular lymphocytic arteritis (MLA) is a benign cutaneous arteritis reported by Fein, et al 1 . MLA could be considered a non-nodule-forming variant or a less aggressive form of cutaneous polyarteritis nodosa 2,3 .…”

mentioning

confidence: 99%