Custom made bioceramic implants in complex and large cranial reconstruction: A two-year follow-up

Staffa, Guido; Barbanera, Andrea; Faiola, Andrea; Fricia, Marco; Limoni, P.; Mottaran, Ruggero; Zanotti, Bruno; Stefini, Roberto

doi:10.1016/j.jcms.2011.04.014

Cited by 92 publications

(58 citation statements)

References 23 publications

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“…60 patients received these implants and were followed-up for 2 years. [28] Similar implants were designed in CAD with and manufactured using the SLA photo polymerization process. The material used was a combination of resin and HA powder.…”

Section: The Process Flowmentioning

confidence: 99%

3D modeling, custom implants and its future perspectives in craniofacial surgery

Parthasarathy¹

2014

Ann Maxillofac Surg

306

220

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Custom implants for the reconstruction of craniofacial defects have gained importance due to better performance over their generic counterparts. This is due to the precise adaptation to the region of implantation, reduced surgical times and better cosmesis. Application of 3D modeling in craniofacial surgery is changing the way surgeons are planning surgeries and graphic designers are designing custom implants. Advances in manufacturing processes and ushering of additive manufacturing for direct production of implants has eliminated the constraints of shape, size and internal structure and mechanical properties making it possible for the fabrication of implants that conform to the physical and mechanical requirements of the region of implantation. This article will review recent trends in 3D modeling and custom implants in craniofacial reconstruction.

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Section: The Process Flowmentioning

confidence: 99%

3D modeling, custom implants and its future perspectives in craniofacial surgery

Parthasarathy¹

2014

Ann Maxillofac Surg

306

220

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“…44-46 Self-setting CaP paste is commonly troweled into large cranial defects over a titanium mesh to provide additional stiffness 1, 4 or pre-operatively prepared via the use of skull models. 47 The fragility of HA, however, precludes its isolated use for large deficits.…”

Section: Advances In Alloplastic Bone Substitutes For Cranial Repairmentioning

confidence: 99%

“…Until recently, preoperative fabrication was achieved manually, using topographical information lacking precision. 48, 49 Although infection remains the most cited reason for implant revision or removal, 46, 47 poor fit nonetheless represents a crucial area for improvement. Fortunately, the recent revolution in 3-D printing has made its way to cranioplasty graft design, thereby vastly improving the “fit” of premade cranial grafts.…”

Section: Advances In Pre-operative Cranial Implant Fabricationmentioning

confidence: 99%

The Recent Revolution in the Design and Manufacture of Cranial Implants

et al. 2015

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Large format (i.e., > 25 cm2) cranioplasty is a challenging procedure not only from a cosmesis standpoint, but also in terms of ensuring that the patient's brain will be well-protected from direct trauma. Until recently, when a patient's own cranial flap was unavailable, these goals were unattainable. Recent advances in implant Computer Aided Design and 3-D printing are leveraging other advances in regenerative medicine. It is now possible to 3-D-print patient-specific implants from a variety of polymer, ceramic, or metal components. A skull template may be used to design the external shape of an implant that will become well integrated in the skull, while also providing beneficial distribution of mechanical force distribution in the event of trauma. Furthermore, an internal pore geometry can be utilized to facilitate the seeding of banked allograft cells. Implants may be cultured in a bioreactor along with recombinant growth factors to produce implants coated with bone progenitor cells and extracellular matrix that appear to the body as a graft, albeit a tissue-engineered graft. The growth factors would be left behind in the bioreactor and the graft would resorb as new host bone invades the space and is remodeled into strong bone. As we describe in this review, such advancements will lead to optimal replacement of cranial defects that are both patient-specific and regenerative.

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“…Cost, however, remains a large barrier to increased utilization of such materials. 6,64,84,112 Other limitations include the increased propensity to fracture due to transfer of CSF pulsations through the dura mater, elevated complication rates in the setting of trauma, and use of hydroxyapatite in areas of potential communication with the sinuses. 74,109,129 plastics…”

Section: Ceramicsmentioning

confidence: 99%

Evolution of cranioplasty techniques in neurosurgery: historical review, pediatric considerations, and current trends

Feroze

Walmsley

Choudhri

et al. 2015

JNS

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Cranial bone repair is one of the oldest neurosurgical practices. Reconstructing the natural contours of the skull has challenged the ingenuity of surgeons from antiquity to the present day. Given the continuous improvement of neurosurgical and emergency care over the past century, more patients survive such head injuries, thus necessitating more than ever before a simple, safe, and durable means of correcting skull defects. In response, numerous techniques and materials have been devised as the art of cranioplasty has progressed. Although the goals of cranioplasty remain the same, the evolution of techniques and diversity of materials used serves as testimony to the complexity of this task. This paper highlights the evolution of these materials and techniques, with a particular focus on the implications for managing pediatric calvarial repair and emerging trends within the field.

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Custom made bioceramic implants in complex and large cranial reconstruction: A two-year follow-up

Cited by 92 publications

References 23 publications

3D modeling, custom implants and its future perspectives in craniofacial surgery

3D modeling, custom implants and its future perspectives in craniofacial surgery

The Recent Revolution in the Design and Manufacture of Cranial Implants

Evolution of cranioplasty techniques in neurosurgery: historical review, pediatric considerations, and current trends

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