Curriculum design for training applied students of biopharmaceutical engineering based on the product life cycle

Abstract

Biopharmaceutical engineering is a newly established undergraduate degree in China, and a lot of issues regarding students' training remain to be explored and refined, particularly the curriculum reflecting the industrial needs for students with applied (hands-on) skills, which has been limited. To narrow the gap between industrial demands and students' training and to provide undergraduates with rational curriculum, in the present investigation, we proposed to reconstruct the curriculum system for applied (hands-on) training of undergraduates of biopharmaceutical engineering based on the life cycle of medicinal products for the first time. A total of 52 subjects on the curriculum were selected and included in different stages of the medicinal products life cycle. After surveying from a recruitment website and biopharmaceutical enterprises, eight applied positions, including drug screening engineer, cell culture engineer, molecular biology technician, fermentation engineer, microorganism engineer, protein purification engineer, protein analysis technician and bio-preparation engineer, were then selected. According to the requirements of each position, 31 subjects were finally chosen from the above-mentioned 52 subjects that are involved in the life cycle of medicinal products. These subjects belong to four clusters and constitute the basis of the curriculum system for applied training of undergraduates of biopharmaceutical engineering. The results obtained from this work are expected to provide evidence for the training of biopharmaceutical students as well as the implementation of collaborative education between university and industry.