Current trends in spinal dysraphism

Humphreys, Robin P.

doi:10.1038/sc.1991.10

Cited by 7 publications

(2 citation statements)

References 24 publications

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“…This defect allows CSF to leak caudally but prevents its ascension into cerebral cavity as the CSF flow is impeded by herniated tonsils of cerebellum. A study conducted by Mary J Seller 1987, on neural tube defects has shown an overall ratio of M:F 0.73 with female excess [6]. @Our study is of similar conclusion.…”

Section: Discussionsupporting

confidence: 86%

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Surgical outcome of myelomeningocele repair associated with Chiari type II malformation

Sanasiya

Joshi

Solanki

2022

ijhs

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Introduction: Meningomyelocele, more commonly known as spina bifida (open) is a congenital malformation of the central nervous system and is associated with significant morbidity. Myelomeningocele is a commonly seen congenital birth defect in children. The most common associations with myelomeningocele are hydrocephalus and ACM Type 2. Folic acid deficiency and parental consanguinity appear to play a major part in this type of congenital defects. Objectives: To analyse the clinical profile and outcome of surgery in cases of myelomeningocele associated with Arnold Chiari malformation II and hydrocephalus. Methods: A Retrospective Cohort study was done starting from January 2015 to January 2019 in the Department of Neurosurgery at SBKS Medical College. Total 18 patients with Myelomeningocele associated with Arnold Chiari malformation II and Hydrocephalus were analysed and evaluated. Follow up of cases was done for a minimum period of 6 months. Results: Out of 18 total cases, the majority of cases, i.e., 76.8%, had myelomeningocele with Chiari II malformation and hydrocephalus. Ratio of females to males was 1.14. Prenatal folic acid supplementation was missed amongst 80% of the cases. 16.6% cases had positive parental consanguinity. Mortality was seen in 2 cases due to post operative complications. Myelomeningocele (MMC)

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Section: Discussionsupporting

confidence: 86%

“…The recurrence rate in subsequent pregnancies is about 2% to 3%. [6]. Spina bifida can also be associated with Arnold Chiari type II malformation which is characterized by downward displacement of the cerebellar tonsils and medulla.…”

Section: Introductionmentioning

confidence: 99%