Current Trends in Sample Treatment Techniques for Environmental and Food Analysis

Lucci, Paolo; Pacetti, Deborah; Núñez, Óscar; Frega, Natale G.

doi:10.5772/47736

Cited by 10 publications

(13 citation statements)

References 111 publications

(121 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…On the other hand, MIPs have long since known to be attractive in this regard. Figure 1 [21] shows the chromatograms (red line) which illustrates the efficiency of the molecularly imprinted polymer-solid-phase extraction (MIP-SPE) procedure (extraction rate of about 90%) and the advantages of both the concentration and sample clean-up with very low background and no interferences close to the retention time of 17β-estradiol.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Molecularly Imprinted Polymers for Pharmaceutical Compounds: Synthetic Procedures and Analytical Applications

Madikizela¹,

Tavengwa²,

Pakade³

2018

Recent Research in Polymerization

View full text Add to dashboard Cite

In this chapter, the synthetic procedures for molecularly imprinted polymers (MIPs) for pharmaceutical compounds are discussed. Regardless of its limitations, such as production of irregular particles and loss of sample during processing (crushing and sieving), bulk polymerization has been widely used compared to say precipitation and suspension polymerization partly due to its simplicity in synthesis and robustness. A comparison of indomethacin removal from aqueous solution by MIP particles prepared using bulk polymerization to those obtained from suspension polymerization showed that the particles from the former exhibited higher adsorption capacity. Furthermore, the chapter explores the strengths and limitations relating the use of pharmaceutical compounds as uni-templates, multi-templates and dummy templates. Also, the analytical applications of MIPs are discussed in more details with particular focus on molecularly imprinted solid-phase extraction (MISPE) of pharmaceuticals from environmental samples. This application (MISPE) is currently the most exploited in literature as more pharmaceutical drugs find their way into environmental water bodies.

show abstract

Section: Introductionmentioning

confidence: 99%

“…This further implies that other ordinary cheap instruments can be used for environmental analysis beside the mass spectrometry (MS) detection that is known to have low detection limits and can detect pharmaceuticals at trace levels. with 17β-estradiol (-) and before MIP clean-up (-) [21].…”

Section: Introductionmentioning

confidence: 99%

Molecularly Imprinted Polymers for Pharmaceutical Compounds: Synthetic Procedures and Analytical Applications

Madikizela¹,

Tavengwa²,

Pakade³

2018

Recent Research in Polymerization

View full text Add to dashboard Cite

show abstract

“…Solid-phase extraction (SPE) is the most popular sample preparation technique for environmental, food and biological samples, and is replacing conventional techniques because it reduces or completely eliminates solvent consumption in analytical procedures [14]. In SPE, sample extraction, pre-concentration and clean-up can be achieved in a single step by selecting an appropriate type of sorbent.…”

mentioning

confidence: 99%

Development of an aflatoxin B1 specific molecularly imprinted solid phase extraction sorbent for the selective pre-concentration of toxic aflatoxin B1 from child weaning food, Tsabana

Semong¹,

Batlokwa²

2017

Molecular Imprinting

View full text Add to dashboard Cite

This paper presents the synthesis, optimization and application of a molecularly imprinted polymer (MIP) sorbent for the selective extraction and pre-concentration of the potent toxin, aflatoxin B1 (AFB1), from the child weaning food, Tsabana (manufactured in Serowe, Botswana). As a food safety regulatory measure, Tsabana must be cleared of hazardous aflatoxins, especially AFB1, before consumption. This is because AFB1 is the most common and potent of the aflatoxins commonly found in cereals. Accurate analysis of AFB1 is challenging because it exists in very low concentrations in complex, ‘dirty’ matrices such as food, making it difficult to detect using analytical instruments, even if these analytical techniques have sensitivities at the femto level. The MIP extraction sorbent synthesized in this paper deals with these challenges by selectively pre-concentrating AFB1 from real Tsabana samples, successfully achieving a pre-concentration factor of 5 and therefore significantly increasing ABF1 signal intensity for easier detection. Further advantages of this system include the short time (25.0 minutes) and reasonable optimal MIP dose (20.0 mg) needed for maximum AFB1 extraction by the sorbent. Scanning electron microscopy revealed that the prepared AFB1 powder particles have spherical geometries and reasonably small sizes (800 nm), two advantageous physical characteristics that are associated with excellent sorbent materials.

show abstract

“…In summary, MIPs appears as a very useful and promising approach for 383 sample extraction and clean-up procedure in bio-analytical applications, where a very high degree 384 of selectivity may be required to reduce analysis time without suffering from problems related to 385 sensitivity of MS detection such as matrix effects. RAMs in automated sample preparation 386 systems on-line coupled with sensitive techniques such as LC-MS/MS or LC-fluorescence have 387 been an effective strategy to overcome that analytical challenge [88][89][90] [96]. But aside from these well-established sorbents, important steps forward 400 in the development of new RAM sorbents have taken place as it is following described.…”

mentioning

confidence: 99%

State-of-the-art in fast liquid chromatography–mass spectrometry for bio-analytical applications

Núñez

Gallart-Ayala

Martins³

et al. 2013

Journal of Chromatography B

Self Cite

View full text Add to dashboard Cite

Current Trends in Sample Treatment Techniques for Environmental and Food Analysis

Cited by 10 publications

References 111 publications

Molecularly Imprinted Polymers for Pharmaceutical Compounds: Synthetic Procedures and Analytical Applications

Molecularly Imprinted Polymers for Pharmaceutical Compounds: Synthetic Procedures and Analytical Applications

Development of an aflatoxin B1 specific molecularly imprinted solid phase extraction sorbent for the selective pre-concentration of toxic aflatoxin B1 from child weaning food, Tsabana

State-of-the-art in fast liquid chromatography–mass spectrometry for bio-analytical applications

Contact Info

Product

Resources

About