Current trends in polyhydroxyalkanoates (PHAs) biosynthesis: Insights from the recombinant Escherichia coli

Production of Short Chain Length Polyhydroxyalkanoates by Bacillus megaterium PHB29 from Starch Feed Stock

“…Most PHAs have been produced by prokaryotic microorganisms, including bacteria, cyanobacteria and archaea (Panda et al, 2005;Quillaguaman et al, 2005;Leong et al, 2014). Bacteria coming under the genera Bacillus are well known for their ability to accumulate poly-3-hydroxybutyrate (PHB) which is the most common and simplest form of PHA with 3-hydroxybutyrate (C 4 ) monomers.…”

Genome Structure ofBacillus cereustsu1 and Genes Involved in Cellulose Degradation and Poly-3-Hydroxybutyrate Synthesis

“…A large number of microorganisms have been found to accumulate PHA as lipoidic storage materials in the cytosol [14][15][16][17]. These microorganisms are mainly divided into four classes (I, II, III, and IV) based on the type of PHA synthases, which are the key enzymes for PHA biosynthesis [18].…”

Heterologous Expression of Various PHA Synthase Genes in Rhodospirillum rubrum

“…Polyhydroxyalkanoates (PHAs) could be a forward-looking alternative to petrochemical-based plastics since they are biobased, biodegradable, biocompatible, and derived from renewable resources 1,2,3,4 . PHAs are synthesized by more than 300 different microorganisms as storage of carbon and energy, if an excess of carbon source is available but an essential nutrient is limited at the same time 5,6,7 . The most commonly accumulated and best studied PHA is polyhydroxybutyrate (PHB) 7 .…”

“…PHAs are synthesized by more than 300 different microorganisms as storage of carbon and energy, if an excess of carbon source is available but an essential nutrient is limited at the same time 5,6,7 . The most commonly accumulated and best studied PHA is polyhydroxybutyrate (PHB) 7 . Due to their elastomeric and thermoplastic character, PHAs have attracted much industrial attention for economic usage 8 .…”