Current trends in pathogenesis, management, bacteriology, and antibiotic resistance in deep neck space infections: An institutional review

Tiwana, Harsimran; Gupta, Swati; Prakash, Devina; Panda, Naresh; Chetan, Bavini; Angrup, Archana; Ray, Prabhati; Bakshi, Jaimanti; Mohindra, Satyawati; Gupta, Richa; Virk, Ramandeep Singh; Verma, Roshan; Bansal, Sandeep; Ramavat, Anurag Snehi; Nayak, Gyanaranjan

doi:10.4103/aiao.aiao_19_19

Cited by 5 publications

(10 citation statements)

References 18 publications

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“…The bacterial culture did not grow in about 42.9% of subjects. The result is similar with the study by Tiwana et al 22 that reported 42.6% of cultured specimens were found to be sterile; this could be due to the use of high-dose intravenous antibiotics or empiric antibiotics before abscess drainage. As for the examination of anaerobic bacteria, there are limitations in the examination at this research institution due to limited reagents so that they were often declared as sterile or not growing.…”

Section: Discussionsupporting

confidence: 91%

“…This study found a significant difference between the average length of stay of patients with positive culture, and there was a positive significant relationship with the length of stay and also found that there was a relationship between dental infection by Streptococcussp and other bacteria on the length of stay of deep neck abscess patients. Tiwana et al 22 reported a bacteriological growth pattern in patients with necrotizing fasciitis compared to deep neck abscesses. In the pre-antibiotic era, the most frequently isolated organism from deep neck space abscess aspiration was Staphylococcus aureus.…”

Section: Discussionmentioning

confidence: 99%

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Factors associated with the length of stay of deep neck abscess patients

Yanti

Lubis

Bahar

et al. 2022

Oto Rhino Laryn Indones

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Background: Deep neck abscess is an accumulation of pus in one or more potential spaces of the deep neck fascia. Complications of deep neck abscesses are considered as an emergency in the Ear Nose Throat–Head and Neck field. One determining factor of prognosis in deep neck abscess patients is the length of stay in the hospital. Objective: To find out the factors associated with the hospital length of stay of deep neck abscess patients. Method: Observational research using a cross sectional design. Data collection was carried out using medical record data on 91 subjects diagnosed with deep neck abscess at Dr. Mohammad Hoesin Hospital Palembang from July 2018 to May 2021. Result: From the 91 samples studied, the average hospital length of stay for deep neck abscess patients was 11.26 days. The study found factors related to the length of stay in the hospital, namely comorbidities (p=0.005), location of the abscess (p=0.004), pus culture (p=0.003), and the number of deep-neck spaces involved (p=0.005). Linear regression found that the most significant factors on the hospital length of stay were the involvement of abscess in 2 or more deep neck spaces (p = 0.002) and the presence of comorbidities (p = 0.005). Conclusion: Abscess involvement in 2 deep neck spaces or more and the presence of comorbidities were the most influential factors associated with the hospital length of stay in deep-neck abscess patients.ABSTRAKLatar Belakang: Abses leher dalam adalah akumulasi pus pada satu atau lebih ruang potensial fasia leher dalam sebagai akibat penjalaran infeksi. Komplikasi abses leher dalam masih merupakan keadaan darurat di bidang THT-KL. Salah satu faktor penentu prognosis adalah lama rawat di rumah sakit. Banyak faktor yang dapat mempengaruhi lama rawat pasien abses leher dalam di rumah sakit. Tujuan: Untuk mengetahui faktor-faktor yang berhubungan dengan lama rawat pasien abses leher dalam di RSUP Dr. Mohammad Hoesin Palembang. Metode: Penelitian observasional yang menggunakan rancangan potong lintang. Pengumpulan data dilakukan dengan menggunakan data rekam medis pada 91 subjek dengan diagnosis abses leher dalam di RSUP Dr. Mohammad Hoesin Palembang periode Juli 2018 sampai dengan Mei 2021. Hasil: Dari 91 sampel yang dilakukan penelitian, rerata lama rawat di rumah sakit pada pasien abses leher dalam adalah 11,26 hari. Penelitian mendapatkan faktor yang berhubungan dengan lama rawat di rumah sakit yaitu komorbid (p=0,005), lokasi abses (p=0,004), kultur pus (p=0,003), dan jumlah ruang leher dalam yang terlibat (p=0,005). Dari uji regresi linier didapatkan faktor yang paling memengaruhi lama rawat di rumah sakit adalah keterlibatan abses ³ 2 ruang leher dalam (p=0,002) dan terdapat komorbid (p=0,005). Kesimpulan: Keterlibatan abses pada 2 ruang leher dalam atau lebih, dan terdapatnya komorbid adalah faktor yang paling berpengaruh terhadap lama rawat pasien abses leher dalam.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Factors associated with the length of stay of deep neck abscess patients

Yanti

Lubis

Bahar

et al. 2022

Oto Rhino Laryn Indones

View full text Add to dashboard Cite

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“…Also, the close proximity of this space to the airway and various communicating pathways to other regions can lead to critical complications such as empyema, mediastinitis, pericarditis, jugular-vein thrombosis, septic shock, respiratory distress, disseminated intravascular coagulation and dissemination 1 unless diagnosed and managed promptly. 2,3 A thorough knowledge of the anatomy as well as the microbiological profile and antibiotic sensitivity is imperative to institute the appropriate surgical and medical management to the patient. Surgical management by incision and drainage and immediate airway management remains the mainstay of treatment.…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Evaluation of Antibiotic Sensitivity in Deep Neck Space Infections

Singhal

Nayak

Padiyar

et al. 2023

IJRSMS

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Background Deep neck space infections (DNIs) are a major medical concern in the Indian community. Owing to the complex anatomy of the neck spaces and their communication with each other, accurate diagnosis becomes challenging. A thorough knowledge of the anatomy as well as the microbiological profile and antibiotic sensitivity is imperative to institute the appropriate surgical and medical management to the patient. Due to the advent of broad-spectrum antibiotics, the incidence of these infections have declined considerably over the last couple of decades. However, due to the extensive and unregulated use, the incidence of antibiotic resistance has also been increasing at an alarming pace. Materials and Methods This cross-sectional observational study was conducted in the Department of Otorhinolaryngology at a tertiary care government hospital in an urban area. All patients who presented to the OPD or emergency over a period of 18 months and who fulfilled the eligibility criteria were included in the study. Pus was collected from the abscess, aseptically by needle aspiration using wide bore (18G) needle and transported under all aseptic measures within 24 hours for culture and sensitivity, KOH mount, and detection of AFB. Antibiotic sensitivity testing was done using the Kirby Bauer disc diffusion method and E-test. Results Staphylococcus aureus as the most common infective organism followed by MRSA in the pediatric age group and Klebsiella pneumoniae in adults. Conclusion Primary knowledge of individual antibiotic sensitivity is imperative to ensure prompt and adequate treatment of the patient with higher chances of complete resolution, concomitantly minimizing the risk of resistance. Inadequate and delayed treatment may lead to swift progression of the disease with significant morbidity and mortality.

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“…[4][5] Despite the decreasing incidence and mortality of deep neck abscess due to the discovery of penicillin and improved dental care, this condition still poses challenges in terms of early diagnosis and management to avoid fatal complications. 6 Several factors influence the success of managing deep neck abscess. These factors include age, gender, socioeconomic status, abscess location, etiology, and comorbidities.…”

Section: Introductionmentioning

confidence: 99%