Current treatment modalities of breast-cancer patients in Alexandria, Egypt

Abdel-Fattah, Moataz M.; Lotfy, Nashaat; Bassili, Amal; Anwar, M.; Mari, E.; Bedwani, R; Tognoni, Gianni

doi:10.1054/brst.2000.0285

Cited by 7 publications

(18 citation statements)

References 17 publications

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“…In Arab countries, the data also show similar trends with a rate of advanced or metastatic stage reaching 60 to 80% of cases [1]. In Egypt, stages III and IV constitute 68% of all breast cancer cases [1, 19, 20]. As for Saudi Arabia, stages III and IV constitute about 46% of cases [21].…”

Section: Clinical Presentation and Pathologymentioning

confidence: 79%

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Breast Cancer in Low- and Middle-Income Countries: An Emerging and Challenging Epidemic

Tfayli

Temraz

Mrad

et al. 2010

Journal of Oncology

115

100

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Breast cancer is a major health care problem that affects more than one million women yearly. While it is traditionally thought of as a disease of the industrialized world, around 45% of breast cancer cases and 55% of breast cancer deaths occur in low and middle income countries. Managing breast cancer in low income countries poses a different set of challenges including access to screening, stage at presentation, adequacy of management and availability of therapeutic interventions. In this paper, we will review the challenges faced in the management of breast cancer in low and middle income countries.

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Section: Clinical Presentation and Pathologymentioning

confidence: 79%

“…Mastectomy rates in Arab countries are high amounting to 79.9%–82% in Egypt, 65% in Oman, 70% among Palestinians, 88% in Syria, and 82.4% in Tunisia [1, 20, 22, 24–26]. In other LMCs, the picture is very similar.…”

Section: Adequacy Of Managementmentioning

confidence: 99%

Breast Cancer in Low- and Middle-Income Countries: An Emerging and Challenging Epidemic

Tfayli

Temraz

Mrad

et al. 2010

Journal of Oncology

115

100

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“…Albeit reluctantly, some studies (mostly hospital-based retrospective studies) had presented limited clinicopathologic data with wide variations that do not capture the national profile. For example, age at diagnosis of BC ranged from 47.8 15 to 57 years, 16 while percentage of T1 tumors ranged from 5% 15 to 26%. 17 …”

Section: Introductionmentioning

confidence: 99%

Clinicopathologic Features of Breast Cancer in Egypt—Contemporary Profile and Future Needs: A Systematic Review and Meta-Analysis

Azim

Elghazawy

Ghazy

et al. 2023

JCO Global Oncology

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PURPOSE Breast cancer (BC) is the most common cancer among Egyptian females. No current national cancer database is available in Egypt to provide reliable data on the specific clinicopathologic features of BC in this population. Herein, we investigated the clinical profile of BC among Egyptian women. METHODS A systematic review of studies on BC published from inception until December 2021 was performed. We explored pooled estimated proportions of different stages of BC at presentation in Egypt and other clinicopathologic features including age, menopausal status, tumor (T) and lymph node (N) stages, and biological subtypes. Data analysis was performed using meta package (R). RESULTS Twenty-six studies were eligible for our systematic review and meta-analysis, including 31,172 BC cases. In 12 studies, including 15,067 patients with BC, the estimated mean age was 50.46 years (95% CI, 48.7 to 52.1; I2, 99%), with a pooled proportion of premenopausal/perimenopausal women of 57% (95% CI, 50 to 63; I2, 98%). Among 9,738 patients with BC, pooled proportions of stage I, II, III, and IV were 6% (95% CI, 4 to 8; I2, 90%), 37% (95% CI, 31 to 43; I2, 93%), 45% (95% CI, 42 to 49; I2, 78%), and 11% (95% CI, 9 to 15; I2, 87%), respectively. The pooled proportions of patients with T3 and T4 tumors were 21% (95% CI, 14 to 31; I2, 99%) and 8% (95% CI, 5 to 12; I2, 96%), respectively, while those with positive lymph nodes were 70% (95% CI, 59 to 79; I2, 99%). CONCLUSION Dominance of advanced stage and young age at diagnosis represented the two main features of BC among Egyptian women. Our data may serve to guide the policymakers in Egypt as well as other countries with lower resources to prioritize the diagnostic and therapeutic needs in this context.

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“…The combination of BSE and CBE seems to be an important available alternative in slum areas [11]. In areas where access to CBE and mammograms is difficult, BSE still detects BC early enough for treatment options.BC is usually diagnosed at an advanced stage in Egypt, and studies revealed that population screening is rarely practiced in Egypt [9,[12][13][14]. Women living in slum areas suffer from the unavailability of services and poor health [15].…”

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confidence: 99%

Raising the Breast Health Awareness amongst Women in an Urban Slum Area in Alexandria, Egypt

Kharboush

Ismail

Kandil³

et al. 2011

Breast Care

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Background: Breast Cancer (BC) is the most frequently occurring cancer among Egyptian women. This study aimed to determine the effectiveness of a health education program on raising the knowledge related to BC, its risk factors, and some related preventive practices among women living in an urban slum area in Alexandria. Patients and Methods: A pre-/post-test interventional study was conducted during 2009–2010 on a random sample of women aged 30–65 years (n = 486) living in a slum area in Alexandria, Egypt. 20 health education sessions were carried out to educate the women on BC risk factors and some preventive practices. Previously trained nurses educated the sampled women on breast self-examination (BSE). The women’s knowledge and opinion about BC and their practice of BSE were evaluated before and 3 months after the intervention. Results: The findings indicated a significant increase in the mean knowledge score regarding BC and the mean opinion score regarding some BC risk factors. A significant increase in the practice of BSE was observed post intervention. Conclusion: This study confirms the effectiveness of intervention programs in improving the knowledge about BC risk factors and practice of BSE even in a group of women with a low literacy rate living in a slum area.

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Current treatment modalities of breast-cancer patients in Alexandria, Egypt

Cited by 7 publications

References 17 publications

Breast Cancer in Low- and Middle-Income Countries: An Emerging and Challenging Epidemic

Breast Cancer in Low- and Middle-Income Countries: An Emerging and Challenging Epidemic

Clinicopathologic Features of Breast Cancer in Egypt—Contemporary Profile and Future Needs: A Systematic Review and Meta-Analysis

Raising the Breast Health Awareness amongst Women in an Urban Slum Area in Alexandria, Egypt

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