Current techniques in peritoneal dialysis

Ross, Linda; Labato, Mary Anna

doi:10.1111/vec.12035

Cited by 18 publications

(15 citation statements)

References 49 publications

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“…Their main indications are for management of acute kidney injury or acute on chronic kidney disease. 177,178 The ISFM welcomes endorsement of these Guidelines by the American Association of Feline Practitioners (AAFP).…”

Section: Dialysis Therapymentioning

confidence: 99%

ISFM Consensus Guidelines on the Diagnosis and Management of Feline Chronic Kidney Disease

Sparkes¹,

Caney²,

Chalhoub

et al. 2016

Journal of Feline Medicine and Surgery

125

157

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In preparing these Guidelines, the Panel has carefully reviewed the existing published literature, and has also graded the quality of evidence for different interventions to help to provide practical recommendations on the therapeutic options for feline CKD. This is a field of veterinary medicine that has benefited from some excellent published clinical research and further research findings will undoubtedly modify the recommendations contained in these Guidelines in the future.

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Section: Dialysis Therapymentioning

confidence: 99%

ISFM Consensus Guidelines on the Diagnosis and Management of Feline Chronic Kidney Disease

Sparkes¹,

Caney²,

Chalhoub

et al. 2016

Journal of Feline Medicine and Surgery

125

157

View full text Add to dashboard Cite

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“…This technique has previously been reported as a way to provide renal replacement support, but the patency of these catheters may be of short duration. 24,26 In this case, the catheter worked appropriately for 36 h, allowing rapid stabilization of pH, and concentrations of urea, creatinine and potassium prior to surgery. In human neonates, a similar technique has been reported in a case series where a 14 G single-lumen central venous catheter, serving as a peritoneal dialysis catheter, was inserted by the Seldinger technique with minimal complications.…”

Section: Discussionmentioning

confidence: 99%

Successful resolution of urothorax secondary to non-traumatic uroabdomen in a cat managed with peritoneal dialysis as a bridge to surgery

Donati¹,

Londoño

Fravega³

et al. 2021

Journal of Feline Medicine and Surgery Open Reports

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Case summary A 9-year-old neutered male domestic shorthair cat was presented for evaluation of severe hemodynamic collapse and suspected lower urinary tract disease. On admission, severe metabolic acidosis, hyperkalemia and azotemia, and electrocardiographic findings consistent with cardiotoxicity were identified. The diagnosis of uroabdomen was made based on abdominal fluid to plasma concentration ratios of creatinine and potassium. A central line catheter was placed percutaneously into the abdomen for peritoneal drainage and used for peritoneal dialysis as a bridge to surgery. Retrograde contrast cystography confirmed rupture of the urinary bladder. Point-of-care ultrasound of the chest postoperatively revealed the presence of mild pleural effusion. Echocardiography was then performed showing no evidence of cardiac disease. Pleural fluid analysis revealed a transudate with a creatinine ratio of 2.38 ([Creatinine]pleural fluid/[Creatinine]plasma), consistent with the diagnosis of urothorax. The cat recovered uneventfully from surgery and was monitored for signs of respiratory distress during the rest of its stay in hospital. The cat was discharged 4 days later and the pleural effusion resolved without further medical intervention. Relevance and novel information There is limited information on the causes of urothorax and uroabdomen management of feline patients. Pleural effusion is a complication observed in critically ill cats secondary to fluid overload, underlying cardiomyopathy, primary thoracic pathology or a combination of these. To our knowledge, this is the first report of urothorax in a cat secondary to non-traumatic uroabdomen. Careful monitoring of respiratory signs consistent with pleural space disease is recommended in cases of uroabdomen.

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“…The tube was covered by a rubber balloon. The ileum was put into a plastic bag with 1 L peritoneal replacement fluid, containing Na + (146.26 mmol/L), K + (4 mmol/L), Ca 2+ (2.22 mmol/L), Cl − (154.76 mmol/L), HCO 3 − (35.05 mmol/L), and glucose (154.5 mg/dL) [34] and kept on ice for transport.…”

Section: Methodsmentioning

confidence: 99%

Establishment of a model for equine small intestinal disease: effects of extracorporeal blood perfusion of equine ileum on metabolic variables and histological morphology – an experimental ex vivo study

et al. 2019

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BackgroundIn horses a number of small intestinal diseases is potentially life threatening. Among them are Equine Grass Sickness (EGS), which is characterised by enteric neurodegeneration of unknown aetiology, as well as reperfusion injury of ischaemic intestine (I/R), and post-operative ileus (POI), common after colic surgery. The perfusion of isolated organs is successfully used to minimize animal testing for the study of pathophysiology in other scenarios. However, extracorporeal perfusion of equine ileum sourced from horses slaughtered for meat production has not yet been described. Therefore the present study evaluated the potential of such a model for the investigation of small intestinal diseases in an ex vivo and cost-efficient system avoiding experiments in live animals.ResultNine ileum specimens were sourced from horses aged 1–10 years after routine slaughter at a commercial abattoir. Ileum perfusion with oxygenated autologous blood and plasma was successfully performed for 4 h in a warm isotonic bath (37.0–37.5 °C). Ileum specimens had good motility and overall pink to red mucosa throughout the experiment; blood parameters indicated good tissue vitality: 82 ± 34 mmHg mean arterial partial pressure of oxygen (pO2) compared to 50 ± 17 mmHg mean venous pO2, 48 ± 10 mmHg mean arterial partial pressure of carbon dioxide (pCO2) compared to 66 ± 7 mmHg venous pCO2 and 9.8 ± 2.8 mmol/L mean arterial lactate compared to 11.6 ± 2.7 mmol/L venous lactate. There was a mild increase in ileum mass reaching 105 ± 7.5% of the pre-perfusion mass after 4 hours. Histology of haematoxylin and eosin stained biopsy samples taken at the end of perfusion showed on average 99% (±1%) histologically normal neurons in the submucosal plexus and 76.1% (±23.9%) histologically normal neurons in the myenteric plexus and were not significantly different to control biopsies.ConclusionExtracorporeal, normothermic perfusion of equine ileum over 4 h using autologous oxygenated blood/plasma perfusate showed potential as experimental model to test whether haematogenous or intestinal exposure to neurotoxins suspected in the pathogenesis of EGS can induce neuronal damage typical for EGS. Also, this model may allow investigations into the effect of pharmaceuticals on I/R injury, as well as into the pathogenesis of equine POI.

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Current techniques in peritoneal dialysis

Cited by 18 publications

References 49 publications

ISFM Consensus Guidelines on the Diagnosis and Management of Feline Chronic Kidney Disease

ISFM Consensus Guidelines on the Diagnosis and Management of Feline Chronic Kidney Disease

Successful resolution of urothorax secondary to non-traumatic uroabdomen in a cat managed with peritoneal dialysis as a bridge to surgery

Establishment of a model for equine small intestinal disease: effects of extracorporeal blood perfusion of equine ileum on metabolic variables and histological morphology – an experimental ex vivo study

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