Current studies on myofascial pain syndrome

Kuan, Ta Shen

doi:10.1007/s11916-009-0059-0

Cited by 69 publications

(43 citation statements)

References 43 publications

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“…This could, in turn, cause a continuous release and inadequate uptake of calcium ions from the local sarcoplasmic reticulum (SR), producing sustained shortening of sarcomeres. A vicious circle of hypoxia (with release of vasoactive/algogenic substances, responsible for local nociceptor sensitization, and thus, hyperalgesia), failed Ca ++ reuptake from the SR (due to energy impairment), and perpetuation of the contracture ("integrated hypothesis" of the original "energy crisis" hypothesis) would thus be initiated [16].…”

Section: Pathophysiology Of Trigger Pointsmentioning

confidence: 99%

Effects of Treatment of Myofascial Trigger Points on the Pain of Fibromyalgia

Giamberardino

Affaitati

Fabrizio

et al. 2011

Curr Pain Headache Rep

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Myofascial pain syndromes (MPSs) from trigger points (TrPs) and fibromyalgia syndrome (FMS) are common musculoskeletal pain conditions that frequently coexist in the same patients. In recent decades, it has become evident that these entities greatly influence each other's clinical expression. FMS is mainly rooted in the central nervous system, while TrPs have a peripheral origin. However, the nociceptive impulses from TrPs may have significant impact on symptoms of FMS, probably by enhancing the level of central sensitization typical of this condition. Several attempts have been made to assess the effects of treatment of co-occurring TrPs in FMS. We report the outcomes of these studies showing that local extinction of TrPs in patients with fibromyalgia produces significant relief of FMS pain. Though further studies are needed, these findings suggest that assessment and treatment of concurrent TrPs in FMS should be systematically performed before any specific fibromyalgia therapy is undertaken.

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Section: Pathophysiology Of Trigger Pointsmentioning

confidence: 99%

Effects of Treatment of Myofascial Trigger Points on the Pain of Fibromyalgia

Giamberardino

Affaitati

Fabrizio

et al. 2011

Curr Pain Headache Rep

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“…Investigations of myofascial trigger points have focused on alterations in the synaptic cleft of the neuromuscular junction, the spinal cord, and the brain response to myofascial pain [33][34][35]. The motor activity is based on the presence of the nodule or taut band.…”

Section: Myofascial Dysfunctionmentioning

confidence: 99%

Endometriosis and Abdominal Myofascial Pain in Adults and Adolescents

Jarrell

2011

Curr Pain Headache Rep

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Endometriosis and myofascial pain are common disorders with significant impact on quality of life. Increasingly, these conditions are being recognized as highly interconnected through processes that have been described for more than a century. This review is directed to this interconnection through a description of the relationships of endometriosis to proposed mechanisms of pain and chronic pain physiology; the clinical assessment of myofascial representations of this pain; and an approach to the management of these interconnected disorders.

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“…Furthermore, even though no patients in this study had secondary causes of cramps, such as hypovitaminosis D, statin therapy, and cirrhosis, it is possible that local TrP injection produces a limited effect if the patients have such diseases or are taking medication. 32 Therefore larger and controlled studies are needed.…”

Section: Discussionmentioning

confidence: 99%

The Effects of Myofascial Trigger Point Injections on Nocturnal Calf Cramps

Kim

Yoon

2015

The Journal of the American Board of Family Medicine

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Background: The purpose of this study was to elucidate the effects of injection at trigger points on pain and sleep disturbance in patients with nocturnal calf cramps (NCCs).Methods: Patients with NCCs that occurred at least once per week and who had myofascial trigger points (MTrPs) on the gastrocnemius muscles were enrolled in the study for 9 months. At the first visit (T0), we measured the intensity of NCC pain on an 11-point numeric rating scale, recorded the frequency of NCCs, and calculated the Insomnia Severity Index (ISI). We then checked for MTrPs on the gastrocnemius muscles and injected 1-2 mL of 0.25% lidocaine into each of the trigger points. At 1 (T1), 2 (T2), and 4 (T3) weeks after the first visit, we repeated the process performed at T0.Results: Twelve patients completed the treatment schedule and attended the follow-up visits. Mean values of the numeric rating scale pain score, frequency of cramps, and ISI declined significantly at T1, T2, and T3 compared with baseline (all P < .01). Of 12 patients, 10 had clinical insomnia before treatment, and this number decreased significantly to 3 patients at T2 and 1 patient at T3 (P ‫؍‬ .012 and P ‫؍‬ .001, respectively).Conclusions: These preliminary data show that injection at MTrPs in patients with NCCs not only alleviated pain and reduced the frequency of cramps but also lessened the severity of insomnia as measured by the ISI. A larger randomized controlled trial is needed to confirm these findings and determine whether the effect lasts over the long term. (J Am Board Fam Med 2015;28:21-27.)

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Current studies on myofascial pain syndrome

Cited by 69 publications

References 43 publications

Effects of Treatment of Myofascial Trigger Points on the Pain of Fibromyalgia

Effects of Treatment of Myofascial Trigger Points on the Pain of Fibromyalgia

Endometriosis and Abdominal Myofascial Pain in Adults and Adolescents

The Effects of Myofascial Trigger Point Injections on Nocturnal Calf Cramps

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