Current status of development and biomedical applications of peptide-based antimicrobial hydrogels

Qu, Huihui; Yao, Quanfu; Chen, Ting; Wu, Haixia; Liu, Ying; Wang, Cong; Dong, Alideertu

doi:10.1016/j.cis.2024.103099

Advances in Colloid and Interface Science

2024

DOI: 10.1016/j.cis.2024.103099

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Current status of development and biomedical applications of peptide-based antimicrobial hydrogels

Huihui Qu,

Quanfu Yao,

Ting Chen

et al.

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2024

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Cited by 4 publications

References 221 publications

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Tailoring supramolecular antimicrobial peptides: from self-assembled nanoarchitectures to activities

Wang,

Wu,

Tian

et al. 2024

Sci. China Mater.

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Tailoring supramolecular antimicrobial peptides: from self-assembled nanoarchitectures to activities

Wang,

Wu,

Tian

et al. 2024

Sci. China Mater.

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Research progress of natural polysaccharide-based and natural protein-based hydrogels for bacteria-infected wound healing

Xu,

Che,

Zhou

et al. 2024

Chemical Engineering Journal

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Antimicrobial Peptides and Their Biomedical Applications: A Review

Min,

Kim,

et al. 2024

Antibiotics

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The emergence of drug resistance genes and the detrimental health effects caused by the overuse of antibiotics are increasingly prominent problems. There is an urgent need for effective strategies to antibiotics or antimicrobial resistance in the fields of biomedicine and therapeutics. The pathogen-killing ability of antimicrobial peptides (AMPs) is linked to their structure and physicochemical properties, including their conformation, electrical charges, hydrophilicity, and hydrophobicity. AMPs are a form of innate immune protection found in all life forms. A key aspect of the application of AMPs involves their potential to combat emerging antibiotic resistance; certain AMPs are effective against resistant microbial strains and can be modified through peptide engineering. This review summarizes the various strategies used to tackle antibiotic resistance, with a particular focus on the role of AMPs as effective antibiotic agents that enhance the host’s immunological functions. Most of the recent studies on the properties and impregnation methods of AMPs, along with their biomedical applications, are discussed. This review provides researchers with insights into the latest advancements in AMP research, highlighting compelling evidence for the effectiveness of AMPs as antimicrobial agents.

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Current status of development and biomedical applications of peptide-based antimicrobial hydrogels

Cited by 4 publications

References 221 publications

Tailoring supramolecular antimicrobial peptides: from self-assembled nanoarchitectures to activities

Tailoring supramolecular antimicrobial peptides: from self-assembled nanoarchitectures to activities

Research progress of natural polysaccharide-based and natural protein-based hydrogels for bacteria-infected wound healing

Antimicrobial Peptides and Their Biomedical Applications: A Review

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