Current Status of Colorectal Cancer and Its Public Health Burden in Thailand

Tiankanon, Kasenee; Aniwan, Satimai; Rerknimitr, Rungsun

doi:10.5946/ce.2020.245-iden

Cited by 8 publications

(6 citation statements)

References 25 publications

(37 reference statements)

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“…Yet, because screening of CRC in young adults is not routine, the number may be an underestimation of the true regional prevalence. 22,23 Our findings align with previous studies in Asia, showing that the rise in early-onset CRC incidence is not exclusive to Western countries. 24,25 The observed increase in early-onset CRC in the Asia-Pacific region may be attributed to various factors, including heightened exposure to CRC carcinogens at a younger age.…”

Section: Discussionsupporting

confidence: 90%

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Rising incidence and impact of early‐onset colorectal cancer in the Asia‐Pacific with higher mortality in females from Southeast Asia: a global burden analysis from 2010 to 2019

Danpanichkul,

Moolkaew,

Kanjanakot

et al. 2023

J of Gastro and Hepatol

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Background and AimEarly‐onset colorectal cancer (CRC) is a growing global health concern, especially in the Asia‐Pacific region. However, comprehensive research on this topic from the region is lacking. Our study aims to investigate trends in early‐onset CRC in Asia over 10 years, filling this research gap.MethodsThis study utilized data from the Global Burden of Disease Study 2019 to assess temporal trends in early‐onset CRC in the Asia‐Pacific. The analysis included estimating annual frequencies and age‐standardized rates (ASRs) of early‐onset CRC incidence, death, and disability‐adjusted life‐years (DALYs) by gender.ResultsThe incidence of early‐onset CRC significantly increased in both regions with higher increase and in the Western Pacific region. Notable increases were observed among males in the Western Pacific and females in Southeast Asia (SEA). Mortality rates remained stable in the Western Pacific but increased by 10.6% in SEA, especially among females. DALYs due to CRC also increased significantly in SEA, with a greater rise among females. The Western Pacific had the highest CRC incidence, and in SEA, the mortality rate was higher in females than males.ConclusionsOur study reveals a substantial increase in early‐onset CRC in the Asia‐Pacific underscoring the urgency for effective interventions. Thus, a comprehensive approach comprising controlled risk reduction, health promotion to heightened disease awareness, and implementation of effective screening strategies should be executed timely to mitigate the burden of early‐onset CRC.

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Section: Discussionsupporting

confidence: 90%

“…The results of the study are concerning, showing the rising incidence rates of early‐onset CRC in both the Western Pacific and SEA regions. Yet, because screening of CRC in young adults is not routine, the number may be an underestimation of the true regional prevalence 22,23 …”

Section: Discussionmentioning

confidence: 99%

Rising incidence and impact of early‐onset colorectal cancer in the Asia‐Pacific with higher mortality in females from Southeast Asia: a global burden analysis from 2010 to 2019

Danpanichkul,

Moolkaew,

Kanjanakot

et al. 2023

J of Gastro and Hepatol

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“…VHVs and local health personnel have contributed to the primary healthcare screening and control for several diseases, for example, tuberculosis, dengue infection, parasitic diseases, cancer screening and prevention, elderly care, and obesity management. 22 - 28 Even recently, their contribution was clearly shown in the fight against COVID-19. 29 Nevertheless, reports of improved control of CKD, DM, and HT by VHVs-central care were limited.…”

Section: Discussionmentioning

confidence: 99%

Integrated Care Model by the Village Health Volunteers to Prevent and Slow down Progression of Chronic Kidney Disease in a Rural Community, Thailand

Theeranut,

Methakanjanasak,

Lertsinudom

et al. 2024

J Prim Care Community Health

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Introduction: Chronic kidney disease (CKD) is a major health problem in Thailand and health behaviors are central to its risk and progression. Because of the shortage of healthcare personnel, village health volunteers (VHVs) have been collaborating in the primary health care system. However, the contribution of VHVs to CKD reduction has not been evaluated yet. This study aimed to evaluate the efficacy of the VHV-integrated model in preventing and slowing down CKD and its risk factors. Methods: The population-based cohort study was conducted in a rural community of Thailand between 2017 and 2019. Baseline clinical and behavioral characteristics including CKD, diabetes, hypertension, and other high-risk factors of the participants were collected. The integrated care model was initiated by the multidisciplinary care team that facilitated, empowered, and trained VHVs targeting risk factors of CKD, health literacy, and health promotion. Then the participants were educated and trained for lifestyle modification and were monitored continuously for 18 months by VHVs. Changes in the CKD risk factors, and kidney functions before and after the application of integrated care model were compared. Results: A total of 831 subjects participated in the study with an average age of 57.5 years, and 69.5% were female. Among them, 222 participants (26.7%) were diagnosed as having CKD, the vast majority (95%) of which were in the early stages (G1-G3 and A1-A2). CKD risk factors such as high salt intake, smoking, alcohol consumption, self-NSAID (non-steroidal anti-inflammatory drugs) use were significantly decreased after application of the care model. Also, hemoglobin A1c was significantly reduced in diabetic patients, and blood pressure was controlled better than before in the hypertensive patients. Most importantly, a decline of estimated glomerular filtration rate of the CKD group was improved and lower than the non-CKD group. Conclusion: The integrated care model through VHV significantly attenuated the risk factors associated with CKD in the general and high-risk population and effectively slowed down the progression of CKD.

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“…The cost-effectiveness and budget impact analyses revealed that colonoscopy was more cost-effective in a low-and middle-income country, with an Incremental Cost-Effectiveness Ratio (ICER) of United States Dollars (USD) 646.5/Quality-Adjusted Life Year (QALY) gained (28). However, providing a nationwide screening colonoscopy can be a challenge in Thailand due to low numbers of endoscopists, less than 1,000 for an estimated number of cases requiring CRC screening of 14 million (29). Hence, a population-based one-step screening colonoscopy program is less likely to succeed in resource-limited countries with a shortage of endoscopists.…”

Section: Discussionmentioning

confidence: 99%

An Assessment of Physicians’ Recommendations for Colorectal Cancer Screening and International Guidelines Awareness and Adherence: Results From a Thai National Survey

et al. 2022

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BackgroundColorectal cancer (CRC) screening uptake is generally low in the Asia Pacific and physicians’ recommendations affect the screening participation.ObjectiveThe study aimed to assess Thai physicians’ recommendations for CRC screening, and the awareness of and adherence to international guidelines.MethodsA survey containing questions assessing physicians’ demographic data, screening recommendations, and awareness of the international CRC screening guidelines assessed by clinical vignettes. Independent predictors of physicians’ recommendations for CRC screening were determined by logistic regression analysis.ResultsFive hundred and eighty-sixth of 1,286 (46%) physicians completed the survey, and 58% of them offered CRC screening. The majority of colorectal surgeons (91%) and gastroenterologists (86%) endorsed screening, whereas 35% of primary care physicians recommended screening. The patient’s age was the only factor influencing the physician’s decision to offer CRC screening (OR, 2.75: 95% CI, 1.61–4.67). Colonoscopy was the most recommended modality among specialists, whereas 60% of primary care physicians offered fecal occult blood tests (FOBTs). The guidelines awareness was noted in 81% of participants, with the highest rates among gastroenterologists and colorectal surgeons. Gastroenterologists were more likely to adhere to the guidelines than surgeons, but both recommended shorter interval surveillance colonoscopy than guidelines recommendations in cases of small hyperplastic rectosigmoid polyps.ConclusionsRecommendations for CRC screening and awareness of guidelines vary among different specialties. A low proportion of primary care physicians recommended screening and colorectal surgeons and gastroenterologists recommended shorter intervals for surveillance of small hyperplastic polyp than suggested by guidelines.

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Current Status of Colorectal Cancer and Its Public Health Burden in Thailand

Cited by 8 publications

References 25 publications

Rising incidence and impact of early‐onset colorectal cancer in the Asia‐Pacific with higher mortality in females from Southeast Asia: a global burden analysis from 2010 to 2019

Rising incidence and impact of early‐onset colorectal cancer in the Asia‐Pacific with higher mortality in females from Southeast Asia: a global burden analysis from 2010 to 2019

Integrated Care Model by the Village Health Volunteers to Prevent and Slow down Progression of Chronic Kidney Disease in a Rural Community, Thailand

An Assessment of Physicians’ Recommendations for Colorectal Cancer Screening and International Guidelines Awareness and Adherence: Results From a Thai National Survey

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