Current status and prospect for future advancements of long-acting antibody formulations

Tyagi, Puneet; Harper, Garrett; McGeehan, Patrick; Davis, Shawn P.

doi:10.1080/17425247.2023.2219445

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Addressing Challenges and Future Directions: Mabs As The The...1

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“…These factors can affect the long-term stability and injectability of the drug [55]. Kinetic studies and modeling data enable the optimization of dosage formulation and play a crucial role in understanding how aggregation may occur during storage [56]. Achieving a therapy with the desired effect that is also practical in storage and administration is a complex engineering task requiring careful consideration for each specific therapy [57].…”

Section: Addressing Challenges and Future Directions: Mabs As The The...mentioning

confidence: 99%

Monoclonal War: The Antibody Arsenal and Targets for Expanded Application

Rosenn,

Benhaim,

Siegel

et al. 2023

Immuno

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Advancements in sequencing and screening technology have made monoclonal antibodies more accessible, cost-effective, and precise. These drugs effectively target pathogens and cancer cells and even regulate metabolic pathways by focusing on specific intermediates. Monoclonal antibodies play a key role in mitigating a rise in occupation-related cancers, neurodegenerative disorders, and multidrug-resistant organisms. Here, we review the origins, mechanisms, and applications of this important drug class and explore future avenues for research.

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Section: Addressing Challenges and Future Directions: Mabs As The The...mentioning

confidence: 99%