2010
DOI: 10.1093/eurjhf/hfq120
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Current state of knowledge on aetiology, diagnosis, management, and therapy of peripartum cardiomyopathy: a position statement from the Heart Failure Association of the European Society of Cardiology Working Group on peripartum cardiomyopathy

Abstract: Peripartum cardiomyopathy (PPCM) is a cause of pregnancy-associated heart failure. It typically develops during the last month of, and up to 6 months after, pregnancy in women without known cardiovascular disease. The present position statement offers a state-of-the-art summary of what is known about risk factors for potential pathophysiological mechanisms, clinical presentation of, and diagnosis and management of PPCM. A high index of suspicion is required for the diagnosis, as shortness of breath and ankle s… Show more

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Cited by 914 publications
(1,131 citation statements)
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References 78 publications
(173 reference statements)
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“…Some of them are Myocarditis, Cardiotropic viral infections [8] Apoptosis and Inflammation [9], and an abnormal hemodynamic response [10]. The European Society of Cardiology defined peripartum cardiomyopathy is a form of dilated cardiomyopathy with signs of heart failure in the last month of pregnancy or within six months of delivery [11]. Increased blood volume and cardiac output may precipitate heart failure symptoms such as dyspnea, dizziness, pedal edema, and orthopnea during pregnancy [12].…”
Section: Discussionmentioning
confidence: 99%
“…Some of them are Myocarditis, Cardiotropic viral infections [8] Apoptosis and Inflammation [9], and an abnormal hemodynamic response [10]. The European Society of Cardiology defined peripartum cardiomyopathy is a form of dilated cardiomyopathy with signs of heart failure in the last month of pregnancy or within six months of delivery [11]. Increased blood volume and cardiac output may precipitate heart failure symptoms such as dyspnea, dizziness, pedal edema, and orthopnea during pregnancy [12].…”
Section: Discussionmentioning
confidence: 99%
“…PPCM is a heart failure syndrome confined to late pregnancy and the postpartum period 13. In mid‐to‐late pregnancy, cardiac output is maintained, primarily due to an increase in heart rate and a decrease in afterload.…”
Section: Discussionmentioning
confidence: 99%
“…It is a diagnosis of exclusion when no other cause of heart failure is found. The LV may not be dilated, but the LVEF is nearly always reduced below 45% [6]. PPCM is rare but a major cause of maternal death, accounting for 4% -25% of cases [7] In this case, we initially ruled out PPCM because she had severe AR before pregnancy.…”
Section: Discussionmentioning
confidence: 99%