Current sickle cell screening program for newborns in New York City, 1979-1980.

Grover, Ranjeet; Shahidi, Syad; Fisher, B; Goldberg, D.; Wethers, Doris L.

doi:10.2105/ajph.73.3.249

Cited by 38 publications

(15 citation statements)

References 8 publications

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“…Parental education and aggressive clinical intervention contributed importantly to improved survival among children diagnosed at birth. Previous studies in the US and elsewhere reported mortality rates as high as 14% within the first 2 years of life compared to less than 2% among infants whose families received education and counseling 7–9.…”

Section: Newborn Screeningmentioning

confidence: 89%

Advances in the management of sickle cell disease

Thompson

2005

Pediatric Blood & Cancer

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This article summarizes my presentation at the Pediatric Hematology-Oncology Symposium in honor of Dr. Stephen A. Feig in April 2005. Areas highlighted reflect key topics whose evolution parallel and were impacted by Steve's exceptional academic career. It is by no means an exhaustive summation of all advances in the biology and treatment of sickle cell disease. The interested reader is encouraged to consider a number of well written recently published reviews that cover additional areas of scientific and medical advancement in the pathophysiology and care of sickle cell disease 1-5.

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Section: Newborn Screeningmentioning

confidence: 89%

Advances in the management of sickle cell disease

Thompson

2005

Pediatric Blood & Cancer

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“…While 2,190 parents of 1,531 trait newborns were tested and counseled successfully during a one-year period, a large number of families (3,034) were not followed. Several factors account for this outcome: 1,365 trait families identified from the 12 undecided hospitals were not notified during this period; many families had moved away before being contacted; and others did not respond for reasons unknown.…”

Section: Discussionmentioning

confidence: 99%

Newborn screening for hemoglobinopathies: the benefit beyond the target.

Grover¹,

Newman²,

Wethers³

et al. 1986

Am J Public Health

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As a result of New York State's Newborn Screening Program 4,565 neonates with trait hemoglobinopathies were identified and 3,200 families were notified of the results of testing their infants in New York City in 1982. Ofthe 1,531 families (2,190 parents) tested and counseled, 22 parents were diagnosed with sickle cell disease and 39 couples were found to be at-risk for having a child with sickle cell disease. Amniocentesis was performed in 14 of the 28 at-risk pregnant women and three of the four affected pregnancies were terminated. (Am J Public Health 1986; 76:1236-1237

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“…(3) daily penicillin prophylaxis in children under 5 years old, (4) prompt investigation and treatment of infectious crises, and (5) follow-up in a comprehensive sickle cell disease program. [4][5][6]26 ACUTE RED CELL DESTRUCTION OR SEQUESTRATION-With these syndromes. the patient's circulating hemoglobin level falls.…”

Section: Roger Thomas Tate Holbrookmentioning

confidence: 99%