Current separative strategies used for resveratrol determination from natural sources

Stir bar sorptive extraction with gas chromatography–mass spectrometry for the determination of resveratrol, piceatannol and oxyresveratrol isomers in wines

“…When both salts were added at different amounts in the interval corresponding to 0.5-2 neutralizing equivalents, higher sensitivity was obtained for all the analytes with 1 and 2 equivalents of Na 3 PO 4 and Na 2 HPO 4 , respectively. Since stilbenoids are very sensitive to pH, being decomposed at high pH values [7,33], the stability of the analytes in the resulting buffered solution should be considered. The responses of the analytes were monitorized when time gaps, between the end of the derivatization step and the start of the SBSE extraction, of between 0 and 2 h were applied under the most favourable conditions.…”

“…These stilbenoids exist naturally in two isomeric forms, the more stable trans-(E) and the less stable cis-(Z), whose isomerization can be achieved by heating or irradiation with intense UV light. The cis-resveratrol isomer is sensitive to atmospheric oxidation, and is only stable at neutral pH and when completely protected from light [7].…”

“…Taking into account the beneficial properties of these species, efficient and sensitive methods are necessary for their determination [7]. Stilbenoids are generally determined by liquid chromatography (LC) using different detection systems, such as UV [11][12][13][14], fluorescence [15][16][17] or mass spectrometry [11,[18][19][20].…”

A Powerful Analytical Strategy Based on QuEChERS-Dispersive Solid-Phase Extraction Combined with Ultrahigh Pressure Liquid Chromatography for Evaluating the Effect of Elicitors on Biosynthesis of trans-Resveratrol in Grapes

“…For instance, solvent extraction (using ethyl acetate or diethyl ether) have been used to isolate trans-resveratrol from grapes and wines (Romero-Pérez et al 2001;Cantos et al 2003;Sun et al 2006;Bavaresco et al 2007;Gómez-Alonso et al 2007;Bravo et al 2008;Gatto et al 2008). Also, solid-phase extraction (SPE) is used as an alternative to the above extraction type to prevent problems such as incomplete phase separation, recoveries below the limit of quantification, and the consumption of large amounts of solvent (Ratola et al 2004;Fan et al 2011). More recently, miniaturized techniques like microextraction by packed sorbent (MEPS) have been used for the same purpose in order to save time and solvent consumptions during the analysis and to improve sensitivity (Gonçalves and Câmara 2011;Sagratini et al 2012).…”

Rapid determination of trans-resveratrol in vegetable oils using magnetic hydrophilic multi-walled carbon nanotubes as adsorbents followed by liquid chromatography–tandem mass spectrometry

“…The common procedures are saponification, liquid-liquid extraction, solid-phase extraction, molecularly imprinted polymers, and solid-phase microextraction (Cai, Koziel, Dharmadhikari, & Hans van Leeuwen, 2009;Fan et al, 2011;Schwarz et al, 2011). Most of these conventional sample preparation methods are time-consuming, laborintensive, tedious, and also require using organic solvents and large sample volumes.…”