Current research on PONV/PDNV: Practical implications for today’s pharmacist

Ignoffo, Robert J.

doi:10.2146/ajhp080457

Cited by 4 publications

(1 citation statement)

References 19 publications

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“…For the purpose of our decision model, costs associated with nausea and vomiting were assumed to involve only the antiemetic drug costs and excluded nominal costs such as emesis basins. Given the current guideline recommendations to use an antiemetic agent from a different pharmacologic class in patients with postoperative nausea and vomiting who do not respond to the first drug, we assumed ondansetron and prochlorperazine, both generically available, as the antiemetic agents used in nausea and vomiting, respectively, and estimated these generic drug prices based on 50% of the average wholesale price…”

Section: Methodsmentioning

confidence: 99%

Economic Analysis of Alvimopan for Prevention and Management of Postoperative Ileus

et al. 2012

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Alvimopan was cost saving for prevention of postoperative ileus in patients undergoing bowel resection by laparotomy, although these potential cost savings were highly dependent on a difference in time to discharge order written. This finding is not applicable to the less-invasive laparoscopic surgical approach for which quality data on alvimopan use are lacking. Limitations of this analysis included use of time to discharge order written as a proxy for length of stay and difficulty interpreting study results due to inconsistent reporting and conduct of the clinical trials evaluating alvimopan. More research is needed to determine the cost-effectiveness of alvimopan.

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Section: Methodsmentioning

confidence: 99%