Current practice of Latin American centers in the treatment of peritoneal diseases with cytoreductive surgery with HIPEC

Background: Cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) has become a valuable treatment strategy for selected patients with peritoneal carcinomatosis (PC). In Chile, it is an emerging technique. The aim of this study is to describe our protocol and report our perioperative results.Methods: A prospectively maintained database for patients undergoing exploratory surgery for PC was reviewed. Eligible patients were selected using the peritoneal cancer index in correlation with the primary tumor. Patients underwent HIPEC using mitomycin C. Clinical data and postoperative results were analyzed.Results: Seventy-six patients underwent exploratory surgery. Most patients were female (55%) with a median age of 62 years (range, 25-83). Complete CRS and HIPEC were achieved in 53 patients. The most frequent primary tumor site was colon-rectum (49%).The median number of resected organs was 4 (range, 1-13). Overall 90-day incidence of major complications was 26%. After a median follow-up of 26 months, 44 patients (83%) in the resected group were alive with no evidence of disease. Conclusions:The PC treatment program at our institution has been established in a safe manner, with acceptable morbidity comparable to high-volume centers. A comprehensive preoperative evaluation, careful patient selection, and a cohesive team are necessary for successful results.

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Starting a peritoneal carcinomatosis treatment program in a developing country: A prospective analysis

Gajardo

Matute

Charles

et al. 2021

Journal of Surgical Oncology

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Peritoneal Mesothelioma: Systematic Review of Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Protocol Outcomes

Képénékian

Sgarbură

Marchal

et al. 2023

Indian J Surg Oncol

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Prognostic Impact of Pathology, Cytoreduction, and Tumor Markers in Pseudomyxoma Peritonei

Lopes

Mello

López

et al. 2022

Journal of Surgical Research

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Current practice of Latin American centers in the treatment of peritoneal diseases with cytoreductive surgery with HIPEC

Cited by 9 publications

References 27 publications

Starting a peritoneal carcinomatosis treatment program in a developing country: A prospective analysis

Starting a peritoneal carcinomatosis treatment program in a developing country: A prospective analysis

Peritoneal Mesothelioma: Systematic Review of Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Protocol Outcomes

Prognostic Impact of Pathology, Cytoreduction, and Tumor Markers in Pseudomyxoma Peritonei

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