Current Management of Urinary Tract Infections

Suwangool, P

doi:10.31524/bkkmedj.2012.02.019

Cited by 2 publications

(2 citation statements)

References 23 publications

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“…Urinary tract infection (UTI) is a common cause of morbidity and mortality affecting all age groups and genders of patients [1]. This infection is caused by uropathogens that invade the urinary tract, the most common being Escherichia coli [2].…”

Section: Introductionmentioning

confidence: 99%

Correlating Urinary Tract Infection with Patients’ Presenting Symptoms and Bacterial Isolation from Urine in Uyo, Nigeria

Abraham¹,

Ekerenam²,

Emmanuel³

2019

SJCM

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Background: In clinical practice, diagnosis of urinary tract infection (UTI) ideally involves the presence of symptoms and a positive urine culture results. However, due to lack of laboratory facility and where present, delays in getting laboratory result encountered by attending outpatient Physicians, diagnosis are made from presenting symptoms in patients. Empirical treatments are commenced with expectation of positive outcome. Objectives: The aim of this study was to correlate Urinary tract infection with presenting symptoms in patients and laboratory culture results from mid-stream urine samples in Uyo, Nigeria. Materials and Methods: This six months descriptive cross sectional study was carried out in the outpatient Department of the University of Uyo Teaching Hospital in Uyo. Data was obtained through questionnaire administered on 370 consenting outpatients and laboratory culture results from collected midstream urine were analyzed using SPSS software (version 20.0). The predisposing risk factors in these patient were also assessed. The midstream urine samples from the subjects were standardly processed. Cultured urine samples that yielded Gram negative uropathogens were further identified using Microbact 24E (Oxoid, UK), while those that yielded Gram positive uropathogens were identified by the appropriate standard procedures. Results: The presenting symptoms were; discomfort when urinating, urge incontinence (7.6%), frequent urination (11.9%), and cloudy urine with foul smell (8.1%), malaise (23.8%), fever (23.5%), back/flank pain (3.8%) and hematuria (4.6%) (P<0.001). The attendant risks factors assessed were age, gender, cleaning method after urination/defecation, contraceptive use, diabetes, past history of UTI and recent catheter use (P<0.05). Female outpatients had more laboratory confirmed UTI (25.9%) than male outpatients (11.5%). Also revealed is the fact that there is higher prevalence of UTI in female outpatients within the reproductive age group of 28-37 years (43.8%). Conclusion: In this study, less than 30% of female patients with presenting symptoms of UTI had positive urine culture test result while only about 12% of males with these symptoms are culture positive for UTI in Uyo,

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Section: Introductionmentioning

confidence: 99%

Correlating Urinary Tract Infection with Patients’ Presenting Symptoms and Bacterial Isolation from Urine in Uyo, Nigeria

Abraham¹,

Ekerenam²,

Emmanuel³

2019

SJCM

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“…UTI is among the most common bacterial infections in humans both in community and hospital settings which occurs in all age groups and in both genders ( Orret & Davis, 2006 ; Omoregie et al, 2008) . UTI is the major cause of morbidity in both the hospital and community settings ( Omigie et al, 2009) and affecting both out and in patients ( Suwangool, 2012 ).…”

Section: Introductionmentioning

confidence: 99%

Urinary Tract Infection among Symptomatic Outpatients Visiting a Tertiary Hospital Based in Midwestern Nigeria

Fd¹

2013

GJHS

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Microbial pathogens implicated in urinary tract infection and their antibiotic susceptibility patterns as prevalent in UTI symptomatic outpatients resident in Benin City, Nigeria was the focus of this study. One hundred (100) midstream urine samples were collected into sterile plastic universal bottles from outpatients who visited the University of Benin Teaching Hospital, Nigeria and who were tentatively diagnosed as manifesting symptoms of UTI. Patients were referred to the Medical Microbiology department by the consulting doctors. Significant bacterial counts and neutrophil (pus cells) counts were carried out on samples by standard methods. Positive samples for both counts were inoculated aseptically on sterile MacConkey agar, Cystine Lactose Electrolyte Deficient (CLED) agar and Sabouraud Dextrose agar plates and incubated appropriately. Microbial isolates were identified and antibiotic sensitivity testing was carried out on isolates by standard methods. Thirty nine (39.0%) and 61 (61.0%) samples recorded significant microbial growth and no growth respectively. Gram negative bacilli constituted 86.1% (of which enterobacteriaceae made up 49.9%) while gram positive cocci made up 13.9%. Strains of uropathogens isolated were Alcaligenes spp (19.4%), Klebsiella aerogenes (16.7%), Escherichia coli (13.9%), Staphylococcus aureus (13.9%), Candida albicans (11.1%), Proteus mirabilis (8.3%), Pseudomonas aeruginosa (5.5%), Enterobacter spp (5.5%) and Providencia spp (5.5%). Occurrence of UTI in male and female patients were 58.3% and 41.7% respectively of which UTI occurred highest in the 25-46, 15-54 and 27-54 age groups in that decreasing order. Alcaligenes spp occurred most in very old female patients. Candida albicans (the only fungal uropathogen) occurred in an 8day old male patient. Other isolates occurred in much older patients. A significantly high microscopic neutrophil count or pyuria was recorded from deposits of UTI positive patients (i.e. < 5/HPF). Eighteen (representing 50.5%) and 15 (47.8%) of total microbial strains isolated were sensitive to nitrofurantoin and ceftriaxone respectively. Antibiotic susceptibility profile also showed 13(41.6%), 13(41.6%), 13(41.6%) for ciprofloxacin, cefuroxime and ofloxacin respectively suggesting moderate sensitivity of the fluoroquinolones and second/third generation cephalosporins. Gentamicin, ampicillin and augmentin recorded over 70.0% resistance level each. A total of nineteen bacterial strains made of E. coli, Enterobacter spp, Proteus mirabilis, Providencia spp, Staph. aureus and Pseudomonas aeruginosa were multi drug resistant as they resisted 3, 3, 4, 4, 5 and 8 antibiotics respectively.

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Current Management of Urinary Tract Infections

Cited by 2 publications

References 23 publications

Correlating Urinary Tract Infection with Patients’ Presenting Symptoms and Bacterial Isolation from Urine in Uyo, Nigeria

Correlating Urinary Tract Infection with Patients’ Presenting Symptoms and Bacterial Isolation from Urine in Uyo, Nigeria

Urinary Tract Infection among Symptomatic Outpatients Visiting a Tertiary Hospital Based in Midwestern Nigeria

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