Current Management of Short Bowel Syndrome

Proposal of intestinal tissue engineering combined with Bianchi’s procedure

“…Therefore, surgeons have tried to improve the problems associated with inadequate bowel length in patients with SBS through creative operative interventions. These procedures were developed in an attempt to optimize the volume-to-surface-area ratio of the intestine to improve the contact time between luminal contents and the absorptive surface [21]. Bianchi's procedure is one such major technique that is occasionally used as surgical therapy for patients with SBS.…”

Short bowel syndrome in children: Surgical and medical perspectives

“…Leak and stricture formation, and risk of injury to intestinal blood supply have been reported. 23,24 With the STEP, anastomotic leak with intestinal perforation typically at the apex of the staple lines has been reported, and it is wise to place a reinforcing suture here to avoid this complication. 25 A retrospective review of a large single-center experience comparing the outcome of Bianchi and STEP in terms of survival, PN weaning, and complications was unable to detect significant differences.…”

Autologous gastrointestinal reconstructive surgery

“…The dilated bowel reduces its caliber taking an accordion shape. Prerequisite for both techniques is a dilatation of the intestinal remnants of at least 4 cm for the STEP procedure [19]. Due to the rarity of the disease and the limited number of patients requiring lengthening procedures only four reports containing data for both LILT and STEP have been published during last few years [20 && ,21-23].…”