Current management of liver diseases and the role of multidisciplinary approach

Abstract

Liver is an organ having extremely diversified functions, ranging from metabolic and synthetic to detoxification of harmful chemicals. The multifunctionality of the liver in principle requires the multidisciplinary and pluralistic interventions for its management. Several studies have investigated liver function, dysfunction and clinic. This editorial work discusses new ideas, challenges and perspectives of current research regarding multidisciplinary and pluralistic management of liver diseases. In one hand the discussions have carried out on the involvement of extracellular vesicles, Na + /H + exchangers, severe acute respiratory syndrome coronavirus 2 and Epstein–Barr virus infections, Drug-induced liver injury, sepsis, pregnancy, and food supplements in hepatic disorders. In the other hand this study has discussed hepatocellular carcinoma algorithms and new biochemical and imaging experiments pertaining to liver diseases. Relevant articles with an impact index value "> 0" from reference citation analysis, which is an open multidisciplinary citation analysis database based on artificial intelligence technology, have served for the study’s argumentation. This work may be a useful tool for the clinical practice and research in managing and investigating liver disorders.

Nomogram for Estimation of Acute Liver Failure Risk in Spontaneous Ruptured Hepatocellular Carcinoma

“…Moreover, opportunistic infections such as cytomegalovirus and Epstein-Barr virus may further exacerbate these processes. 16,17 In light of this, we conducted a study with the objective of developing and validating a novel predictive model for the onset of ALF in SRHCC patients during treatment. This model was based on clinical data gathered over a decade from a large single center.…”

“…Moreover, opportunistic infections such as cytomegalovirus and Epstein-Barr virus may further exacerbate these processes. 16 , 17 …”