Current issues in the practical use of allopurinol in patients with gout and hyperuricemia
M. S. Eliseev
Abstract:The cornerstone of the treatment of gout and hyperuricemia (HU) is the use of urate-lowering drugs, primarily xanthine oxidase inhibitors. Allopurinol, which has been used to treat gout for six decades, is the first line urate-lowering therapy (ULT). However, the principles of ULT prescription, and allopurinol in particular have changed several times. Allopurinol remains the most widely used and highly effective drug in the world for lowering serum uric acid levels, and its prescription in routine clinical pra… Show more
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