Current Insights and future directions in Staphylococcus aureus infections: Advances and Perspectives

Abstract

Staphylococcus aureus infections are a global health concern, causing various illnesses. Recent research has provided insights into the epidemiology and pathogenesis of these infections, including the role of virulence factors and immune evasion strategies. Understanding the genetic mechanisms responsible for resistance is crucial in dealing with antibiotic-resistant strains like MRSA, which is the focus of this chapter. We also explore the advancements in diagnostics and detection methods, such as PCR and whole-genome sequencing and alternative treatments, viz. anti-virulence agents, monoclonal antibodies, and innovative antimicrobial peptides, which have improved patient outcomes. We end the chapter with a focus on the future research required for developing effective vaccines and alternative therapeutics to address the increasing concern of Staphylococcus aureus infections.