Current external and internal exposure to naphthalene of workers occupationally exposed to polycyclic aromatic hydrocarbons in different industries

Abstract

Actual conditions of occupational hygiene at the workplaces investigated in this comprehensive study are better than those that current limit values of 50,000 microg/m3 (TLV, TRK) seem to induce. It has become obvious that tobacco smoking is a crucial confounding factor in biological monitoring of naphthalene-exposed humans, making interpretation of occupationally increased naphthol excretions very difficult at low exposure levels.

Keratinocyte growth factor protects against Clara cell injury induced by naphthalene

“…As reviewed recently, NA is used as feedstock in various chemical industrial processes and is suggested to pose a problem in the workplaces of various industries [6,7]. Hence it is conceivable that therapeutic application of DN23-KGF immediately following accidental occupational exposure to high levels of NA might help to limit the development of severe airway epithelial injury, although additional studies in humans are required before such an approach can be translated into clinics.…”

“…Naphthalene (NA), a harmful environmental toxin, can be found in ambient air, ground water and cigarette smoke and is produced by combustion [6]. NA is used as feedstock in various chemical industrial processes and was suggested to pose a problem in the workplaces of various industries [7]. NA, which has been found to be the most abundant polycyclic aromatic hydrocarbon in sidestream cigarette smoke [8], selectively injures nonciliated Clara cells of the conducting airways.…”

Naphthalin/Naphthole und Human- Biomonitoring

“…Bei erheblichen Schwankungen auch innerhalb derselben Branche können am Arbeitsplatz Naphthalinkonzentrationen von wenigen μg bis zu mehreren mg pro m 3 erreicht werden [10]. In einer aktuellen Untersuchung an verschiedenen Arbeitsplätzen in Deutschland wurden maximal 0,7 mg/m 3 gemessen [18].…”

“…Nach beruflicher Exposition (n = 277) betrug die Konzentration von 1-Naphthol ungefähr das 1,2-Fache der 2-Naphtholwerte [18]. Serdar et al [46] fanden bei Naphthalin-exponierten Arbeitern ebenfalls etwas höhere 1-als 2-Naphtholwerte, bei Kontrollpersonen ein Konzentrationsverhältnis von ungefähr eins.…”

A Catalytic Resonance Fluorometry Method for Determination of Hydroquinone and Its Applications

“…1,2 Therefore, it is significant to determine hydroquinone in environmental samples. 3 At present, the analytical methods for hydroquinone are mainly spectrophotometry, [4][5][6] chemiluminescence analysis, 7,8 electrochemical analysis, [9][10][11][12] chromatography, [13][14][15] and fluorometry. 16,17 Some of these methods are expensive or time-consuming or the organic solvents being used are toxic.…”