2024
DOI: 10.3389/fcell.2024.1346996
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Current developments and opportunities of pluripotent stem cells-based therapies for salivary gland hypofunction

Wenpeng Song,
Huan Liu,
Yingying Su
et al.

Abstract: Salivary gland hypofunction (SGH) caused by systemic disease, drugs, aging, and radiotherapy for head and neck cancer can cause dry mouth, which increases the risk of disorders such as periodontitis, taste disorders, pain and burning sensations in the mouth, dental caries, and dramatically reduces the quality of life of patients. To date, the treatment of SGH is still aimed at relieving patients’ clinical symptoms and improving their quality of life, and is not able to repair and regenerate the damaged salivar… Show more

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