Current Dental Adhesives Systems. A Narrative Review

Abstract

Adhesive dentistry is based on the development of materials which establish an effective bond with the tooth tissues. In this context, adhesive systems have attracted considerable research interest in recent years. Successful adhesive bonding depends on the chemistry of the adhesive, on appropriate clinical handling of the material as well as on the knowledge of the morphological changes caused on dental tissue by different bonding procedures. This paper outlines the status of contemporary adhesive systems, with particular emphasis on chemical characteristics and mode of interaction of the adhesives with enamel and dentinal tissues. Dental adhesives are used for several clinical applications and they can be classified based on the clinical regimen in "etch-and-rinse adhesives" and "self-etch adhesives". Other important considerations concern the different anatomical characteristics of enamel and dentine which are involved in the bonding procedures that have also implications for the technique used as well as for the quality of the bond. Etch-and-rinse adhesive systems generally perform better on enamel than self-etching systems which may be more suitable for bonding to dentine. In order to avoid a possible loss of the restoration, secondary caries or pulp damage due to bacteria penetration or due to cytotoxicity effects of eluted adhesive components, careful consideration of several factors is essential in selecting the suitable bonding procedure and adhesive system for the individual patient situation.

Carious affected dentine: its behaviour in adhesive bonding

“…71,87,88 Although in CAD the hybrid layer of ERAs is thicker than in sound dentine, the reinforcement of intertubular collagen and tubular tags may be compromised. 89 Many factors may interfere with a tight bond in CAD using ERAs. The soft, already demineralized collagen, 90 the high degree of porosity and wetness, 46 a lack of minerals around and within the fibrils, 16 as well as spectral changes in the secondary structure of the collagen, 8 may cause much aggressive etching in CAD.…”

Dental Bonding Agent: Allergy Contact Dermatitis: Report of 3 Cases

“…Therefore, dental professionals are now heavily exposed to the use of these advanced adhesives during their daily routine work [3]. Almost all types of dental bonding agents contain (Meth) acrylates [4].…”

Mechanistic investigations of matrix metalloproteinase-8 inhibition by metal abstraction peptide

“…1 They are crucial for normal biological function, but changes in the levels and activity of MMPs have been associated with a variety of disease states, including cancer metastasis, atherosclerosis, diabetes, periodontal inflammation, pulmonary fibrosis, and tuberculosis. [2][3][4][5][6][7][8] In addition, MMPs have been implicated in the degradation of biomedical implants including dental restorations. 3,4,[8][9][10] MMP-8 degrades collagen and has been shown to be activated and to degrade the tooth structure around dental restorations (specifically the type I collagen in dentin).…”

“…[2][3][4][5][6][7][8] In addition, MMPs have been implicated in the degradation of biomedical implants including dental restorations. 3,4,[8][9][10] MMP-8 degrades collagen and has been shown to be activated and to degrade the tooth structure around dental restorations (specifically the type I collagen in dentin). 8 Regulation of MMP-8 and other matrix metalloproteinases is therefore a significant therapeutic target.…”