Current Concepts in the Pathogenesis and Management of Vascular Lesions - A Brief Review.

S, Dr.SnehanjanSarangi; S, Dr.DebanjaliMukherjee

doi:10.21474/ijar01/3302

Cited by 1 publication

(1 citation statement)

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“…Embryonic origin: According to this theory, periocular hemangiomas are believed to originate during embryonic development. It suggests that abnormal blood vessels develop due to an error or abnormality in the formation of blood vessels during the early stages of fetal development [11]. This is further supported by the location of facial hemangiomas at areas of mesenchymal and ectodermal fusion [12,13].…”

Section: Risk Factors and Etiological Theoriesmentioning

confidence: 96%

Periocular Hemangioma: Clinicopathological Aspects

M. Alkatan,

R. Fatani,

A. Helmi

et al. 2024

Common Childhood Diseases - Diagnosis, Prevention and Management [Working Title]

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Hemangiomas are pathologically considered to be developmental hamartomatous lesions. In the periocular region, capillary hemangioma is commonly encountered in infants and children, and it is of particular importance because of its critical location if involving the eyelid with obstruction of the visual axis. In this chapter, we aim to briefly discuss the pathogenesis and etiology of such lesions, describe the histopathological features, and the diagnostic immunohistochemical stains used, with differentiating features between infantile hemangioma and capillary hemangioma in adults. In the periocular region, the clinical appearance and manifestations depend on three primary locations of the hemangioma: the superficial, subcutaneous, and deep orbital hemangiomas. Treatment options are similar to hemangioma elsewhere, however, as mentioned above, early treatment may be advocated to avoid developing amblyopia (lazy eye) because of visual deprivation or obstruction. The most used therapy in the periocular region is beta-blockers, either orally or locally. Intralesional steroids and sclerosing agents may also be used. Surgical intervention is reserved for deep orbital-selected lesions.

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Section: Risk Factors and Etiological Theoriesmentioning

confidence: 96%