Current clinical framework on nitric oxide role in periodontal disease and blood pressure
Leonel Lima,
Sara Gaspar,
Bárbara S. Rocha
et al.
Abstract:Objectives
In this review, we explored potential associations between NO and its derivatives, nitrite and nitrate, with periodontal and cardiovascular diseases, with special emphasis on the former. By providing a state-of-the-art and integrative understanding of this topic, we aimed to shed light on the potential role of these three nitrogen oxides in the periodontitis-hypertension nexus, identify knowledge gaps, and point out critical aspects of the experimental methodologies.
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