Current Assessments Regarding the Pathogenesis and Treatment Strategies of Oral Lichen Planus – A Review

Singh, Pratyush; Patel, Pratik; Ar, Raghu; Shergill, Ankur Kaur; Solomon, Monica Charlotte

doi:10.21276/apjhs.2014.1.2.11

Cited by 3 publications

(1 citation statement)

References 8 publications

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“…A large body of evidence supports a role of immune dysregulation in the pathogenesis. The various mechanisms hypothesized to be involved in the immunopathogenesis are: [15] •…”

Section: • Graft Versus Host Diseasementioning

confidence: 99%

Title: Reticular oral lichen planus: The intra-oral web - A case report

Pauly¹,

Kashyap²,

Kini³

et al. 2017

Gulhane Med J

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Oral lichen planus (OLP) is a chronic mucosal condition commonly encountered in clinical dental practice. Lichen planus is believed to represent an abnormal immune response in which epithelial cells are recognized as foreign, secondary to changes in the antigenicity of the cell surface. OLP is a chronic inflammatory disease characterized by relapses and remissions. Treatment is aimed primarily at reducing the length and severity of symptomatic outbreaks. Topical steroids are the first-choice agent for the treatment of symptomatic, active OLP.

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“…A large body of evidence supports a role of immune dysregulation in the pathogenesis. The various mechanisms hypothesized to be involved in the immunopathogenesis are: [15] •…”

Section: • Graft Versus Host Diseasementioning

confidence: 99%

Title: Reticular oral lichen planus: The intra-oral web - A case report

Pauly¹,

Kashyap²,

Kini³

et al. 2017

Gulhane Med J

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Sustainable Drug Delivery of Famotidine Using Chitosan‐Functionalized Graphene Oxide as Nanocarrier

et al. 2019

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This work mainly focuses on the graphene oxide (GO)‐assisted sustainable drug delivery of famotidine (FMT) drug. Famotidine is loaded onto GO and encapsulated by chitosan (CH). UV‐visible spectroscopy, field emission scan electron microscopy, and atomic force microscopy confirm the loading of FMT on GO. An interaction of FMT with GO and CH through amine functionalities is confirmed by Fourier‐transform infrared spectroscopy. Differential scanning calorimetric and cyclic voltammetric investigations confirm the compatibility of FMT and its retaining activity within chitosan‐functionalized graphene oxide (CHGO) composite. Encapsulation efficiency of FMT is determined for various CHGO‐FMT combinations and found to be higher at 1:9 ratio. The in vitro drug release profile is studied using a dissolution test apparatus in 0.1 m phosphate buffer medium (pH = 4.5), which shows sustainable drug release up to 12 h, which is greater than the market product (Complete release within 2 h). Comparative study of drug encapsulated with CH and without GO elucidates that GO is responsible for the sustainable release. The “n” value obtained from slope using Korsmeyer–Peppas model suggests the super case‐II transport mechanism.

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Are tumor necrosis factor-α and matrix metalloproteinase-9 able to induce basal cell degeneration and enhance tissue destruction in cutaneous lichen planus?

Elsayed¹,

Ebrahim²

2016

Egyptian Journal of Pathology

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Current Assessments Regarding the Pathogenesis and Treatment Strategies of Oral Lichen Planus – A Review

Cited by 3 publications

References 8 publications

Title: Reticular oral lichen planus: The intra-oral web - A case report

Title: Reticular oral lichen planus: The intra-oral web - A case report

Sustainable Drug Delivery of Famotidine Using Chitosan‐Functionalized Graphene Oxide as Nanocarrier

Are tumor necrosis factor-α and matrix metalloproteinase-9 able to induce basal cell degeneration and enhance tissue destruction in cutaneous lichen planus?

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