Current Applications and Selected Technical Details of Dual-Energy X-Ray Absorptiometry

Sawicki, Piotr; Tałałaj, Marek; Życińska, Katarzyna; Zgliczyński, Wojciech Stefan; Wierzba, Waldemar

doi:10.12659/msm.930839

Cited by 9 publications

(8 citation statements)

References 90 publications

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“…DXA was mainly measured in the axial bone, including the lumbar spine and hip joint. Lumbar measurements include the vertebral body and its posterior adnexal structure, which is in uenced by body size (e.g., obesity) and abdominal aortic calci cation, and does not directly re ect cervical bone density [29][30] . In addition, DXA is not a routine test before cervical surgery, which requires additional costs.…”

Section: Discussionmentioning

confidence: 99%

Lower Hounsfield units on CT are related to 3D-Print Artificial Vertebral Body subsidence after anterior cervical corpectomy and fusion

Mei

Wang

Tian

et al. 2023

Preprint

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Objective The subsidence of vertebral body replacement may occur after cervical spine ACCF surgery, which may lead to cervical kyphosis, spinal cord compression and neurological dysfunction. The author used CT to measure the relationship between HU value and the subsidence of 3D-Print artificial vertebral body(3D-PAVB) after cervical spine ACCF surgery. Methods The data of patients with cervical spondylosis treated by ACCF surgery from 2017 to 2020 in Bethune Hospital of Shanxi were analyzed retrospectively. The statistical data included age, sex, type of cervical spondylosis, body mass index (BMI), disease type, surgical segment, whether to incorporate the ACDF,vertebral height, Cobb Angle, and HU values of vertebral body and endplate. Clinical efficacy was evaluated using VAS, JOA and NDI. Univariate analysis was performed to determine the factors contributing to the subsidence of the 3D-printed artificial vertebra, and independent risk factors were determined by logistic regression. The ROC curve and area under the curve (AUC) were used to analyze the HU value and predict the 3D-PAVB subsidence. Results 66 patients met the inclusion criteria. 19 patients had 3D-PAVB subsidence, the subsidence rate was 28.8%. Postoperative JOA, VAS and NDI scores of patients in the subsidence group and non-subsidence group were significantly improved. Univariate analysis showed statistically significant differences in age, diabetes, smoking and lower vertebral CT values between the two groups. The average HU value of the subsidence group (251.39 ± 52.62, n = 19) was significantly lower than that of the non-subsidence group (317.06 ± 73.59, n = 47, p<0.01). Multivariate analysis confirmed that smoking and HU of the lower vertebra were independent risk factors for 3D-PAVB subsidence, with an AUC of 0.772 and an optimal threshold of 272 for HU (sensitivity 78.9%, specificity 74.5%). Conclusion Smoking and low HU before surgery are independent risk factors for early postoperative 3D-PAVB subsidence. Understanding smoking history before surgery and measuring CT HU value are helpful to predict early 3D-Print artificial vertebral subsidence after cervical spine ACCF surgery. The lower the CT HU value, the higher the subsidence risk.

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Section: Discussionmentioning

confidence: 99%

Lower Hounsfield units on CT are related to 3D-Print Artificial Vertebral Body subsidence after anterior cervical corpectomy and fusion

Mei

Wang

Tian

et al. 2023

Preprint

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“…However, due to its high cost, its use is not yet widespread [ 52 ]. In conclusion, PET, like other methods, has some limitations that are mainly related to patient exposure to both radiopharmaceuticals and ionizing radiation, which can make it problematic to perform studies in healthy populations [ 53 ].…”

Section: Quantitative Imaging Markers Of Body Compositionmentioning

confidence: 99%

“…Dual-energy X-ray absorptiometry (DEXA) is an additional available technique to quantify different tissues in patients. It is a widely accessible, fast, and inexpensive two-dimensional projection technique suitable for assessing body composition by estimating body fat, muscle tissue, and bone mineral density [ 53 , 54 ]. In the context of neoplastic cachexia, DEXA has been used to measure the body and regional distribution of skeletal muscle and VATS [ 20 , 53 , 55 ].…”

Section: Quantitative Imaging Markers Of Body Compositionmentioning

confidence: 99%

“…It is a widely accessible, fast, and inexpensive two-dimensional projection technique suitable for assessing body composition by estimating body fat, muscle tissue, and bone mineral density [ 53 , 54 ]. In the context of neoplastic cachexia, DEXA has been used to measure the body and regional distribution of skeletal muscle and VATS [ 20 , 53 , 55 ]. There are multiple studies in the literature about its use in breast cancer, neuroendocrine tumors, and, in general, on the assessment of muscle dysfunction in cancer patients [ 55 , 56 , 57 ].…”

Section: Quantitative Imaging Markers Of Body Compositionmentioning

confidence: 99%

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Quantitative and Qualitative Radiological Assessment of Sarcopenia and Cachexia in Cancer Patients: A Systematic Review

Mortellaro,

Triggiani,

Mascaretti

et al. 2024

JPM

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Sarcopenia, an extremely common condition in cancer patients, is described as a progressive and generalized musculoskeletal disorder that is associated with an increased likelihood of adverse outcomes, including falls, fractures, physical disability, and mortality. By contrast, cachexia is defined as a syndrome characterized by weight loss with the concomitant loss of muscle and/or fat mass. Cancer cachexia leads to functional impairment, reduced physical performance, and decreased survival, and is often accompanied by cancer progression and reduced response to therapy. The literature states that cancer patients with cachexia or sarcopenia have many more complications than patients without these conditions. The interplay between physiologic sarcopenia and cancer cachexia is, in part, responsible for the complexity of studying wasting disorders in the cancer population, particularly in the geriatric population. For these reasons, a comprehensive assessment of the body composition and physical function of these patients is necessary. There are several modalities adapted to measure skeletal muscle mass, such as dual-energy X-ray absorptiometry (DEXA), bioelectrical impedance analysis (BIA), computed tomography (CT), magnetic resonance imaging (MRI), and ultrasound (US). The gold standard for the measurement of quantitative and qualitative changes in body composition in patients with cancer is the analysis of tissue density using a CT scan. However, this technique remains poorly implemented in clinical practice because of the use of ionizing radiation. Similarly, DEXA, MRI, and US have been proposed, but their use is limited. In this review, we present and compare the imaging techniques that have been developed so far for the nutritional assessment of cancer patients.

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“…However, the development of modern computer technologies and software makes it possible to develop and apply new methods of X-ray densitometry with high visualization of a computer image and accurate digital measurements of images of animal skeleton bones [13][14][15].…”

Section: Introductionmentioning

confidence: 99%

Comparative evaluation of the integrative parameters of the bone tissue of lower limbs of broiler chickens when using osteotropic additives in the diet

Semenenko,

Savinkov,

Vinokurova

et al. 2023

E3S Web of Conf.

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The article presents the results of studies of the comparative assessment of the bone tissue integrative parameters of the lower limbs of broiler chickens of the Arbor Acres cross when using in their diet the drug siliostin and feed additives for correcting mineral metabolism – acidic calcium and bentonite clays of the Kantemirovskoye deposit of the Voronezh region. Based on the measurements of the width of the sum of the cortical zone of the diaphysis of the X-ray images of the bones, the assessment of its average brightness, as well as the assessment of the average brightness of the middle part of the bone, it was found that in hens and cocks of meat poultry during the period of intensive growth and development, the use of various feed mineral additives leads to unequal changes in the structure and degree of mineralization of the femur and tibia bones of the extremities. Moreover, the most stable positive picture of changes was noted in chickens treated with siliostin + acidic calcium. The absence of a stable picture from other radiological parameters should be considered as a part of complex biochemical processes in the body that accompany the growth and development of young poultry.

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Current Applications and Selected Technical Details of Dual-Energy X-Ray Absorptiometry

Cited by 9 publications

References 90 publications

Lower Hounsfield units on CT are related to 3D-Print Artificial Vertebral Body subsidence after anterior cervical corpectomy and fusion

Lower Hounsfield units on CT are related to 3D-Print Artificial Vertebral Body subsidence after anterior cervical corpectomy and fusion

Quantitative and Qualitative Radiological Assessment of Sarcopenia and Cachexia in Cancer Patients: A Systematic Review

Comparative evaluation of the integrative parameters of the bone tissue of lower limbs of broiler chickens when using osteotropic additives in the diet

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