Current and future microbiome-based therapies in inflammatory bowel disease
Jonathan A. Montrose,
Satya Kurada,
Monika Fischer
Abstract:Purpose of review
The role of the microbiome and dysbiosis is increasingly recognized in the pathogenesis of inflammatory bowel disease (IBD). Intestinal microbiota transplant (IMT), previously termed fecal microbiota transplant has demonstrated efficacy in restoring a healthy microbiome and promoting gut health in recurrent Clostridioides difficile infection. Several randomized trials (RCTs) highlighted IMT's potential in treating ulcerative colitis, while smaller studies reported on its applicati… Show more
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