Current and future impact of osteoarthritis on health care: a population-based study with projections to year 2032

Turkiewicz, Aleksandra; Petersson, Ingemar F; Björk, Jonas; Hawker, Gillian; Dahlberg, Leif; Lohmander, L. Stefan; Englund, Martin

doi:10.1016/j.joca.2014.07.015

Cited by 366 publications

(300 citation statements)

References 36 publications

(28 reference statements)

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“…Osteoarthritis (OA) is a well-known global challenge for today's health care system with a far-reaching economic burden to society and consequences for each individual affected by this disease [1,2]. Moreover, there is no known cure and no proven pharmacologic intervention available to treat OA [3,4].…”

Section: Introductionmentioning

confidence: 99%

Validation of scoring hip osteoarthritis with MRI (SHOMRI) scores using hip arthroscopy as a standard of reference

et al. 2018

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Purpose To validate SHOMRI gradings in preoperative hip magnetic resonance imaging (MRI) with intra-arthroscopic evaluation of intraarticular hip abnormalities. Methods Preoperative non-arthrographic 3.0-T MRIs of 40 hips in 39 patients (1 patient with bilateral hip surgery) with femoroacetabular impingement (FAI) syndrome (mean age, 34.7 years ± 9.0; n = 16 females), refractory to conservative measures, that underwent hip arthroscopy were retrospectively assessed by two radiologists for chondrolabral abnormalities and compared with intra-arthroscopic findings as the standard of reference. Arthroscopically accessible regions were compared with the corresponding SHOMRI subregions and assessed for the presence and grade of cartilaginous pathologies in the acetabulum and femoral head. The acetabular labrum was assessed for the presence or absence of labral tears. For the statistical analysis sensitivity and specificity as well as intraclass correlation (ICC) for interobserver agreement were calculated. Results Regarding chondral abnormalities, 58.8% of the surgical cases showed chondral defects. SHOMRI scoring showed a sensitivity of 95.7% and specificity of 84.8% in detecting cartilage lesions. Moreover, all cases with fullthickness defects (n = 9) were identified correctly, and in n = 6 cases (out of n = 36 with partial-thickness defects) the defective cartilage was identified but the actual depth overestimated. Labral tears were present in all cases and the MR readers identified 92.5% correctly. ICC showed a good interobserver agreement with 86.3% (95% CI 80.0, 90.6%) Conclusion Using arthroscopic correlation, SHOMRI grading of the hip proves to be a reliable and precise method to assess chondrolabral hip joint abnormalities. Key Points • Assessment of hip abnormalities using MRI with surgical correlation.• Comparing surgery and MRI by creating a hybrid anatomic map that covers both modalities.• Non-arthrographic use of 3.0-T MRI provides detailed information on cartilage and labral abnormalities in hip joints.

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Section: Introductionmentioning

confidence: 99%

Validation of scoring hip osteoarthritis with MRI (SHOMRI) scores using hip arthroscopy as a standard of reference

et al. 2018

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“…Comparisons of our projections of future OA rates with published projections from other studies are challenging due to differences in populations and methodologies. Turkiewicz et al (15) recently projected the prevalence of any physician-diagnosed OA between 2012 and 2032 among people ages $45 years in an administrative database in Skåne, Sweden. These authors considered both population aging and the impact of obesity.…”

Section: Discussionmentioning

confidence: 99%

“…Since obesity rates have been rising in many parts of the world, including Canada (13,14), incidence of OA may be expected to increase beyond the effect of aging. A recent study from Sweden projected an increase in OA prevalence in people ages $45 years from 26.6% to 29.5% between 2012 and 2032, when the trend in obesity was taken into account (15).…”

Section: Introductionmentioning

confidence: 99%

Effects of Reductions in Body Mass Index on the Future Osteoarthritis Burden in Canada: A Population‐Based Microsimulation Study

Kopeć

Sayre

Finès

et al. 2016

Arthritis Care & Research

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Objective. Osteoarthritis (OA) is the most common joint disease and a major cause of disability. Incidence and prevalence of OA are expected to increase due to population aging and increased levels of obesity. The purpose of this study was to project the effect of hypothetical interventions that change the distribution of body mass index (BMI) on OA burden in Canada. Methods. We used a microsimulation computer model of OA based on the Population Health Model platform. The model used demographic predictions for Canada and population data from an administrative database in British Columbia and national Canadian surveys.Results. Under the base-case scenario, between 2010 and 2030, OA prevalence is expected to increase from 11.5% to 15.6% in men and 16.3% to 21.1% in women. In scenarios assuming, on average, a 0.3-, 0.5-, or 1-unit drop in BMI per year, OA prevalence in 2030 would reach 14.9%, 14.6%, and 14.2% in men and 20.3%, 19.7%, and 18.5%, in women, respectively. Under these scenarios, the proportion of new cases prevented would be 9.5%, 13.2%, and 16.7%, respectively, in men, and 9.1%, 15.2%, and 25.0% in women. Targeting only those people ages ‡50 years for weight reduction would achieve approximately 70% of the impact of a full population strategy. Targeting only the obese (BMI ‡30) would likely result in a larger benefit for men than women. Conclusion. Due to the aging of the population, OA will remain a major and growing health issue in Canada over the next 2 decades, regardless of the course of the obesity epidemic.

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“…[1][2][3][4][5] These damages of the knee cartilage are caused by degenerative changes or trauma of the joint. Due to the demographic trend in western population, but also the increase of competitive and recreational sports, the number of focal cartilaginous injuries is on the rise among young and old population.…”

Section: Introductionmentioning

confidence: 99%

“…Due to the demographic trend in western population, but also the increase of competitive and recreational sports, the number of focal cartilaginous injuries is on the rise among young and old population. [1][2][3][4][5][6][7][8][9][10] Defects of knee cartilage are not only causing chronic pain, decreased function and degeneration, they also lead to early-onset osteoarthritis of the knee, which is one of the diseases with the greatest impact on the economy and patients quality of life in western civilisation. 1,11,12 Present common treatment strategies depending on size and stage are bone marrow stimulation (e.g.…”

Section: Introductionmentioning

confidence: 99%

New approach for predictive measurement of knee cartilage defects with three-dimensional printing based on CT-arthrography: A feasibility study

Michalik

Schrading

Dirrichs

et al. 2017

Journal of Orthopaedics

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Current and future impact of osteoarthritis on health care: a population-based study with projections to year 2032

Cited by 366 publications

References 36 publications

Validation of scoring hip osteoarthritis with MRI (SHOMRI) scores using hip arthroscopy as a standard of reference

Validation of scoring hip osteoarthritis with MRI (SHOMRI) scores using hip arthroscopy as a standard of reference

Effects of Reductions in Body Mass Index on the Future Osteoarthritis Burden in Canada: A Population‐Based Microsimulation Study

New approach for predictive measurement of knee cartilage defects with three-dimensional printing based on CT-arthrography: A feasibility study

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