Current Advances in Keratoconus Imaging

Awwad, Shady T.; Asroui, Lara

doi:10.1007/978-3-030-84506-3_1

Cited by 1 publication

(4 citation statements)

References 68 publications

(93 reference statements)

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“…To overcome the limitations of previous aberrometer technologies, such as aliasing and overlapping spots, a new pyramidal wavefront sensor with a large dynamic range and greater resolution was developed. 6 This study aimed to evaluate the repeatability of the ocular aberrations measured by such pyramidal aberrometers in a sample of normal and keratoconus eyes.…”

Section: Discussionmentioning

confidence: 99%

“…4,5 Alternatively, the recent clinical introduction of the pyramidal aberrometer offers a promising solution, boasting rapid wavefront capture, an extensive dynamic range, and high resolution. 6 Introduced initially in 2002, pyramidal aberrometry was applied for human measurement over a decade ago on the Peramis (Costruzione Strumenti Oftalmici manufactured for Schwind eye-tech-solutions GmbH & Co. KG), also known as Osiris (Costruzione Strumenti Oftalmici) platforms. 6,7 The concept of pyramidal aberrometry hinges on analyzing the infrared light beam that bounces off the retina and using a pyramid-shaped lens to divide this returning light into several beams to create an interference pattern.…”

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confidence: 99%

“…6 Introduced initially in 2002, pyramidal aberrometry was applied for human measurement over a decade ago on the Peramis (Costruzione Strumenti Oftalmici manufactured for Schwind eye-tech-solutions GmbH & Co. KG), also known as Osiris (Costruzione Strumenti Oftalmici) platforms. 6,7 The concept of pyramidal aberrometry hinges on analyzing the infrared light beam that bounces off the retina and using a pyramid-shaped lens to divide this returning light into several beams to create an interference pattern. The analysis of this pattern determines the aberrations and quantifies heir type and magnitude.…”

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confidence: 99%

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confidence: 99%

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Repeatability of Pyramidal Aberrometer Measurements in Keratoconus and Normal Eyes

Ibrahim,

Assaf,

Bejjani

et al. 2024

J Cataract Refract Surg

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PURPOSE: To evaluate the intrasubject repeatability of pyramidal aberrometer measurements in a sample of keratoconus and normal eyes. SETTING: American University of Beirut Medical Center, Beirut, Lebanon. DESIGN: Prospective comparative repeatability analysis. METHODS: Study Population: Keratoconus and Normal eyes from adult patients. Observation Procedures: Each eye was evaluated with 3 consecutive acquisitions using a pyramidal aberrometer. Main Outcome Measures: The repeatability of different ocular Higher Order and Lower Order Aberrations (HOAs and LOAs, respectively), and Zernike coefficients down to the fifth order, was evaluated. Repeatability was assessed by within-subject standard deviations (Sw), repeatability limits (r), and intraclass correlation coefficients (ICC), among other parameters. RESULTS: 72 keratoconus patients (72 eyes), and 76 normal patients (76 eyes) were included. In normal and keratoconus eyes, the ICC of total LOA and HOAs, as well as each of the Zernike coefficients, was >0.9. The Sw for keratoconus eyes with mean maximal keratometry (Kmax)<50D was 0.1345 for total LOAs, 0.0619 for total HOAs, 0.0292 for horizontal coma, 0.0561 for vertical coma, and 0.0221 for spherical aberration as compared to 0.2696, 0.1486, 0.0972, 0.1497 and 0.0757 for Keratoconus eyes with Kmax>=50D. Similar trend of better repeatability for grade 1 keratoconus and HOA<2D as compared to grade 2 and 3 keratoconus and eyes with HOA>2D were also noted. CONCLUSIONS: Ocular aberrometer measurements generated by high definition pyramidal aberrometers have high repeatability in both normal and mild keratoconus eyes; and moderate repeatability, yet still clinically acceptable, in advanced keratoconus. This is of particular importance in ocular wavefront-guided treatments.

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Section: Discussionmentioning

confidence: 99%

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confidence: 99%

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confidence: 99%

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confidence: 99%

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