Current Advances in Corneal Stromal Stem Cell Biology and Therapeutic Applications
Thomas Volatier,
Claus Cursiefen,
Maria Notara
Abstract:Corneal stromal stem cells (CSSCs) are of particular interest in regenerative ophthalmology, offering a new therapeutic target for corneal injuries and diseases. This review provides a comprehensive examination of CSSCs, exploring their anatomy, functions, and role in maintaining corneal integrity. Molecular markers, wound healing mechanisms, and potential therapeutic applications are discussed. Global corneal blindness, especially in more resource-limited regions, underscores the need for innovative solutions… Show more
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