Current Advancements on the Significance of Oncolytic Viruses in the Treatment of Tumor Cells

Abstract

The occurrence and severity of tumor, which is caused by many factors and etiological agents, become rapid and its distribution is worldwide that lead to death of many individuals. In order to avoid associated complications scientists discovered a means for the removal of tumor using oncolytic virus called virotherapy. This review is aiming to give highlight about the current advancements on the significance of oncolytic viruses in the treatment of tumor cells. Oncolytic viruses carry the promise to efficiently target cancer cells for destruction and spread throughout tumor tissue to reach distant loci without causing collateral damage to healthy tissues. Current oncolytic virotherapy strategies are based on the common molecular mechanisms of viral infection and cell transformation, like apoptotic dysregulation and cell cycle disruption. In this regards this time scientists is being done active research to improve the accessibility, safety and efficacy of oncolytic virotherapy.

Estimation of ruminal digestibility and fermentation characteristics of coffee pulp: A meta-analysis of in vitro experiments

“…The next step was to eliminate duplication, screening the title, abstract, and the entire collected articles by sorting out research conducted on in vitro studies on ruminants. A total of six relevant articles were included in this study [9]- [12], [16], [17]. After collecting the data, to allow direct analysis, different measurement units of the parameters were transformed into similar units.…”