Cure of chronic prostatitis presumably due to Enterococcus spp and gram-negative bacteria

Treatment of Bacterial Prostatitis: Clinico-Pharmacological Considerations

“…Linezolid, administered intravenously (600 mg, twice daily), in combination with oral co-trimoxazole (960 mg b.i.d. ), was effective in resolving a complicated case of prostatitis, likely involving both Enterococci and various Enterobacteriaceae [ 50 ].…”

The perspectives of the application of phage therapy in chronic bacterial prostatitis

“…Penicillins, which are used in the therapy of ABP, are not recommended for use in CBP (Benway & Moon, 2008). The first reports about linezolide application in CBP in combination with co‐trimoxazole in the treatment of the E. faecalis infection were positive (Pronk et al , 2006).…”

“…Recent reports suggest a critical role of Gram-positive pathogens in CBP's etiology. The most common are Enterococcus faecalis and Staphylococcus aureus (Nickel & Costerton, 1992;Bergman, 1994;Bundrick et al, 2003;Pronk et al, 2006;Benway & Moon, 2008). The role of coagulase-negative staphylococci and Corynebacterium sp., so far recognized as nonpathogenic, is also discussed (Nickel & Costerton, 1992;Bergman, 1994;Riegel et al, 1995;Nickel, 2000;Bundrick et al, 2003;Pronk et al, 2006;Benway & Moon, 2008).…”

“…The most common are Enterococcus faecalis and Staphylococcus aureus (Nickel & Costerton, 1992;Bergman, 1994;Bundrick et al, 2003;Pronk et al, 2006;Benway & Moon, 2008). The role of coagulase-negative staphylococci and Corynebacterium sp., so far recognized as nonpathogenic, is also discussed (Nickel & Costerton, 1992;Bergman, 1994;Riegel et al, 1995;Nickel, 2000;Bundrick et al, 2003;Pronk et al, 2006;Benway & Moon, 2008). Atypical bacteria such as Chlamydia trachomatis, Mycoplasma hominis, Mycoplasma genitalium, and Ureaplasma urealiticum were also isolated from the genitourinary tracts of CBP patients (Shurbaji et al, 1988;Ohkawa et al, 1993;Potts et al, 2000;Krieger & Riley, 2002;Benway & Moon, 2008).…”

Eradication of Enterococcus faecalis by phage therapy in chronic bacterial prostatitis — case report

“…Gram-positive and anaerobic bacteria are generally discussed as possible causes of CBP, which is most commonly evoked by E. coli but also by Klebsiella spp., Proteus spp., or P. aeruginosa (Wagenlehner et al 2008;Benway and Moon 2008). Recently, however, prostate infection with E. faecalis has been more often considered to be a result of clinical challenge (Pronk et al 2006;van Nieuwkoop et al 2008). Despite the general progress in the diagnostics and pharmacotherapy of prostatitis (e.g., the introduction of chinolones) the results of treatment of its chronic bacterial form are not satisfactory because of the low penetration of active registered antibiotics and chemotherapeutics into the prostate gland.…”